作者： sarah

Strasbourg, France & Tokyo, Japan, Nov 8, 2024 - (JCN Newswire via SeaPRwire.com) - Transgene (Euronext Paris: TNG), a biotech company that designs and develops virus-based immunotherapies for the treatment of cancer, and NEC Corporation (NEC; TSE: 6701), a leader in IT, network and AI technologies, today announced 24.1 month median follow-up data from the ongoing randomized Phase I trial of TG4050 in the adjuvant treatment of head and neck cancers. The data will be presented in a poster at the Society for ImmunoTherapy of Cancer (SITC) 2024 Annual Meeting, November 9.TG4050 is an individualized immunotherapy being developed for solid tumors that is based on Transgene’s myvac® platform and powered by NEC’s cutting-edge AI capabilities designed to optimize antigen selection.After a median follow up of 24.1 months, all 16 patients who received TG4050 as adjuvant immunotherapy after completion of an adjuvant standard of care remain disease-free and have not relapsed. Out of the 16 patients in the control observation arm, 3 patients have relapsed. There remains a high medical need for these head and neck cancer patients, as approximately 30% of them are expected to experience a relapse within 24 months after standard surgery and adjuvant chemoradiotherapy.Immune responses targeting selected neoantigens were identified in 100% of patients who received TG4050, demonstrating the strong immunogenicity of the cancer vaccine, with both de novo and amplified responses. An analysis over 7 months also shows that immune responses are sustained, during the induction and boost periods.All treatment-related adverse events continue to be mild to moderate.Pr. Le Tourneau, Head of the Department of Drug Development and Innovation (D3i) at Institut Curie, and Principal Investigator, said: "It is highly encouraging to see confirmation of TG4050’s clinical and immune response data after a median follow-up of 24.1-months. There remains a significant unmet need in head and neck cancer patients in the adjuvant setting. TG4050 has demonstrated its potential to prime an adaptive immune response against tumor antigens and prevent relapse in patients with locally advanced resected head and neck squamous cell carcinoma."Dr. Emmanuelle Dochy, Chief Medical Officer of Transgene, added: "We are very encouraged to observe that all the patients treated with our neoantigen cancer vaccine TG4050 remain disease-free after a median follow-up of 24.1 months. Looking at these results and at the long-lasting immune response, we are confident that TG4050 has the potential to benefit these patients, who still face a significant risk of relapse with current therapies. A Phase II part of our trial is currently enrolling patients internationally, with the aim of further confirming these promising findings."Motoo Nishihara, Corporate EVP, and CTO, at NEC, added: "These results illustrate the power of our collaboration with Transgene and our ability to develop a personalized approach to cancer patient treatment using our proprietary artificial intelligence and machine learning models. We have built a strong and compelling clinical data set to support the benefits of TG4050 as an individualized immunotherapy, and we remain committed to bringing novel AI-based treatments to patients across the globe."The SITC poster can be viewed in-person during the poster presentation at the SITC 2024 meeting and can be accessed on Transgene’s website on November 9.Building on these promising data, the randomized Phase I trial has been expanded to a randomized Phase I/II trial in the adjuvant setting of head and neck cancer NCT04183166), which is currently enrolling patients in a Phase II part.Poster detailsAbstract Number: 650Title: Randomized phase I trial of adjuvant individualized TG4050 vaccine in patients with locally advanced resected HPV-negative head and neck squamous cell carcinoma (HNSCC)Presenting Author: C. Le Tourneau – Institut CuriePoster Presentation Day: November 9About myvac®myvac® is a viral vector (MVA—Modified Vaccinia Ankara) based, individualized immunotherapy platform that has been developed by Transgene to target solid tumors. myvac®-derived products are designed to stimulate the patient’s immune system to recognize and destroy tumors using their own cancer specific genetic mutations. Transgene has set up an innovative network that combines bioengineering, digital transformation, established vectorization know-how and unique manufacturing capabilities. Transgene has been awarded "Investment for the Future" funding from Bpifrance for the development of its platform myvac®. TG4050 is the first myvac®-derived product being evaluated in clinical trials. Click here to watch a short video on myvac®.About TG4050TG4050 is an individualized immunotherapy being developed for solid tumors that is based on Transgene’s myvac® technology and powered by NEC’s longstanding artificial intelligence (AI) and machine learning (ML) expertise. This virus-based therapeutic vaccine encodes neoantigens (patient-specific mutations) identified and selected by NEC’s Neoantigen Prediction System. The prediction system is based on more than two decades of expertise in AI and has been trained on proprietary data allowing it to accurately prioritize and select the most immunogenic sequences.TG4050 is designed to stimulate the immune system of patients in order to induce a T-cell response that is able to recognize and destroy tumor cells based on their own neoantigens. This individualized immunotherapy is developed and produced for each patient.About the clinical trialTG4050 is being evaluated in a Phase I/II clinical trial for patients with HPV-negative head and neck cancers (NCT04183166). An individualized treatment is created for each patient after they complete surgery and while they receive adjuvant therapy. Half of the participants received their vaccine immediately after completing adjuvant treatment. The other half were given TG4050 as an additional treatment at the time of recurrence of the disease as an additional treatment to standard of care (SoC). This randomized study is evaluating the treatment benefits of TG4050 in patients who are at risk of relapse. In the Phase I part, thirty-two evaluable patients have been included in this trial under way internationally. The Phase II part is currently enrolling patients.About TransgeneTransgene (Euronext: TNG) is a biotechnology company focused on designing and developing targeted immunotherapies for the treatment of cancer. Transgene’s programs utilize viral vector technology with the goal of indirectly or directly killing cancer cells.The Company’s clinical-stage programs consist of a portfolio of therapeutic vaccines and oncolytic viruses: TG4050, the first individualized therapeutic vaccine based on the myvac® platform, TG4001 for the treatment of HPV-positive cancers, as well as BT-001 and TG6050, two oncolytic viruses based on the Invir. IO® viral backbone.With Transgene’s myvac® platform, therapeutic vaccination enters the field of precision medicine with a novel immunotherapy that is fully tailored to each individual. The myvac® approach allows the generation of a virus-based immunotherapy that encodes patient-specific mutations identified and selected by Artificial Intelligence capabilities provided by its partner NEC.With its proprietary platform Invir. IO®, Transgene is building on its viral vector engineering expertise to design a new generation of multifunctional oncolytic viruses.Additional information about Transgene is available at: www.transgene.frFollow us on social media: X (formerly Twitter): @TransgeneSA—LinkedIn: @TransgeneAbout NEC’s Neoantigen Prediction SystemNEC’s neoantigen prediction system utilizes its proprietary AI, such as graph-based relational learning, trained on multiple sources of biological data to discover candidate neoantigen targets. These targets are carefully analyzed using proprietary machine learning algorithms that include in-house HLA binding and antigen presentation AI tools to evaluate the likelihood of eliciting a robust and clinically relevant T-cell response. With NEC OncoImmunity now on board, NEC continues to strengthen its top-class neoantigen prediction pipelines with the aim of maximizing the therapeutic benefits of personalized cancer immunotherapy for patients worldwide.For more information, visit NEC at www.nec.com.For additional information, please also visit NEC OncoImmunity at https://www.oncoimmunity.com/About NEC CorporationNEC Corporation has established itself as a leader in the integration of IT and network technologies while promoting the brand statement of “Orchestrating a brighter world.” NEC enables businesses and communities to adapt to rapid changes taking place in both society and the market as it provides for the social values of safety, security, fairness and efficiency to promote a more sustainable world where everyone has the chance to reach their full potential.For more information, visit NEC at https://www.nec.com and NEC’s AI Drug Development Business at https://www.nec.com/en/global/solutions/ai-drug/ DisclaimerThis press release contains forward-looking statements, which are subject to numerous risks and uncertainties, which could cause actual results to differ materially from those anticipated. The occurrence of any of these risks could have a significant negative outcome for the Company’s activities, perspectives, financial situation, results, regulatory authorities’ agreement with development phases, and development. The Company’s ability to commercialize its products depends on but is not limited to the following factors: positive pre-clinical data may not be predictive of human clinical results, the success of clinical studies, the ability to obtain financing and/or partnerships for product manufacturing, development and commercialization, and marketing approval by government regulatory authorities. For a discussion of risks and uncertainties which could cause the Company’s actual results, financial condition, performance or achievements to differ from those contained in the forward-looking statements, please refer to the Risk Factors ("Facteurs de Risque") section of the Universal Registration Document, available on the AMF website (https://www.amf-france.org) or on Transgene’s website (www.transgene.fr). Forward-looking statements speak only as of the date on which they are made, and Transgene undertakes no obligation to update these forward-looking statements, even if new information becomes available in the future. Copyright 2024 JCN Newswire via SeaPRwire.com.

TOKYO, Nov 7, 2024 - (JCN Newswire via SeaPRwire.com) - Hitachi High-Tech Corporation ("Hitachi High-Tech") and The University of Tokyo ("UTokyo") have been conducting joint research ("this research") into practical applications of high-resolution Laser-PEEM(1) developed by UTokyo in the semiconductor manufacturing process. This research will be presented at MNC 2024 (International Microprocesses and Nanotechnology Conference 2024), which will be held in Kyoto Prefecture from November 12 to 15, 2024.Overview of Laser-PEEMLaser-PEEM can be faster image analysis compared to SEM(2) used in the semi-conductor wafer manufacturingprocess, and observation of the chemical information of materials and the non-destructive observation of three-dimensional structures on the nano-level used high- resolution technology developed by UTokyo. In this research, we conducted trials on the application of Laser-PEEM in the semiconductor field and have verified its effectiveness.We will continue to conduct research in collaboration with UTokyo by understanding the needs of semiconductor manufacturers to help resolve issues in the manufacturing and shipping processes.(1) Laser-PEEM: Laser-Photo Emission Electron Microscope(2) SEM: Scanning Electron MicroscopeBackgroundAs semiconductor device performance has improved with the progress that's been made in miniaturization and high integration, at present, nano-level circuit patterns are being formed using extreme ultraviolet (EUV) lithography. Asdevices become increasingly miniaturized and highly integrated, changes in 3D processing precision of circuit patternsand localized material properties in the manufacturing process have come to have a greater impact on device performance than ever before. For this reason, multi-point and varied inspections and measurements are becoming essential, and the need for improved inspection throughput is expected to continue to increase going forward.Hitachi High-Tech has been conducting joint research with UTokyo since 2020, which developed the high-resolutionLaser-PEEM technology, with the aim of resolving further issues facing customers by leveraging Hitachi High-Tech's expertise in supporting semiconductor manufacturing through high reproducibility and throughput.Details of This Research's Trials Using the Features of High-resolution Laser-PEEM1. Quick nano-scale observationLaser-PEEM irradiates the entire observation target with a laser instead of an electron beam, and obtains the observedimage by capturing the electrons emitted from the observation target with a camera. This research has verified that, using this method, it is possible to obtain a wider area of high-resolution data at once, thereby contributing tosubstantially shortening the inspection process compared to a SEM, which scans using an electron beam.2.  Enables the observation of various chemical information of materialsThe semiconductor manufacturing process consists of three main processes: resist coating, exposure, and development. In order to inspect the shape of circuit patterns, we currently inspect the uneven patterns formed on thewafer surface after development. It is believed that yield could be improved if it were possible to inspect what are called latent image patterns, which are formed immediately after exposure and are chemically etched with no irregularities on the actual surface. In this research, we applied Laser-PEEM to latent image pattern observation anddemonstrated that it was possible to observe them at high resolution and with high throughput. This functionality is a technique that was not possible with SEMs, and we anticipate this could lead to the creation of new inspection markets going forward.3. Enables non-destructive observation of nanostructuresLaser-PEEM is capable of sensing at depths of approximately 10 to 100 nanometers, and we have demonstrated that it is able to "look through" and see whether defects are present in wafers and what caused them in a non-destructive manner. This makes it possible for the previous work of processing wafers to analyze the cause of faults to now be carried out non- destructively. We also expect to see more advances in moving to three-dimensions going forward,thereby contributing to reducing the workload involved in processing, as well as more accurate analysis.Future OutlookBy providing inspection and measurement equipment using electron beam technology and optical technology, Hitachi High-Tech continues to respond to our customers' various processing, measurement and inspection needs in the development and mass production of semiconductor devices. Looking to the future, the combination of this high-resolution technology developed by UTokyo and Hitachi High-Tech's automation and stabilization technology, together with an extensive customer network, will open up new possibilities for applying high-resolution Laser-PEEM in inspections and measurements in the cutting-edge semiconductor manufacturing processes.In addition, we anticipate that Laser-PEEM, which enables the acquisition of even more information from theobservation target, will contribute not only to the semiconductor field, but also to a wide range of industries andfundamental scientific research. As such, we will continue our research in the application of technology toward resolvinga wide range of social issues.We will continue to provide innovative and digitally enhanced solutions to our products for the upcoming technology challenges, and create new value together with our customers, as well as contributing to cutting-edge manufacturing.Related InformationToday, November 7, 2024, the Materials Innovation Research Center (MIRC), the University of Tokyo Collaborative Research Organization, the Institute for Solid State Physics, and the Graduate School of Frontier Sciences have issued a press release related to this research. Please see the link below for details.www.issp.u-tokyo.ac.jp/maincontents/news2.html?pid=24999 (Japanese only)About Hitachi High-TechHitachi High-Tech, headquartered in Tokyo, Japan, is engaged in activities in a broad range of fields, including manufacture and sales of clinical analyzers, biotechnology products, radiation therapy systems, semiconductor manufacturing equipment, analytical instruments, and analysis equipment. Also, we provide high value-added solutions in industrial fields such as mobility, connected, environment and energy, etc. Through business based on our core Observation, Measurement and Analysis technologies, we will contribute to the realization of a sustainable society by solving social issues.The company's consolidated revenues for FY2023 were approx. JPY 670.4 billion. For further information, visit www.hitachi-hightech.com/global/en/Contact:Makoto SakakibaraOpen Business Promotion Dept., Business Strategy Planning Div.,Nano-Technology Solution Business Group, Hitachi High-Tech CorporationEmail: makoto.sakakibara.yf@hitachi-hightech.com Copyright 2024 JCN Newswire via SeaPRwire.com.

TOKYO, Nov 7, 2024 - (JCN Newswire via SeaPRwire.com) - Mitsubishi Motors Corporation (hereafter, Mitsubishi Motors) today announced that it has decided to acquire up to 149,028,300 shares (representing 10.02% of the total number of issued shares, excluding treasury shares) from Nissan Motor Co., Ltd. (hereafter, Nissan), reducing Nissan’s current 34.07% stake (506,620,577 shares) in Mitsubishi Motors.At 8:45 a.m. on November 8, 2024, a consigned purchase order will be placed with the Tokyo Stock Exchange off-auction own share repurchase trading system (ToSTNeT-3) at the price of JPY 460.6 per share, which is the closing price (including final special quote) for today, November 7, 2024 (no changes to other transaction systems or transaction times will be made). The purchase order will be valid at the transaction time specified above.In light of the recent trend to reduce cross-shareholdings, Mitsubishi Motors has decided to repurchase its own shares from Nissan Motor after considering ways to improve capital efficiency and expand shareholder returns.Mitsubishi Motors and Nissan will continue their collaborative efforts to drive innovation and deliver exceptional value to their stakeholders. Together, the Alliance companies are actively engaged in high-value creation projects that respond to evolving industry trends.About Mitsubishi MotorsMitsubishi Motors Corporation (TSE:7211) — a member of the Alliance with Renault and Nissan — is a global automobile company based in Tokyo, Japan, which has about 28,000 employees and a global footprint with production facilities in Japan and the ASEAN region. Mitsubishi Motors has a competitive edge in SUVs, pickup trucks and plug-in hybrid electric vehicles, and appeals to ambitious drivers willing to challenge convention and embrace innovation. Since the production of our first vehicle more than a century ago, Mitsubishi Motors has been a leader in electrification — launched the i-MiEV, the world’s first mass-produced electric vehicle in 2009, followed by the Outlander PHEV, the world’s first plug-in hybrid electric SUV in 2013. With a target of increasing the sales ratio of electrified vehicles to 100% by 2035, Mitsubishi Motors will deliver models that embody Mitsubishi Motors-ness and contribute to the realization of a carbon-neutral society.For more information on Mitsubishi Motors, please visit the company's website at www.mitsubishi-motors.com/en/. Copyright 2024 JCN Newswire via SeaPRwire.com.

TOKYO, Nov 7, 2024 - (JCN Newswire via SeaPRwire.com) - Honda Motor Co., Ltd. (Honda) has signed a sponsorship agreement with World Athletics ahead of the World Athletics Championships Tokyo 25 (WCH Tokyo 25) as an official global partner. Based on this sponsorship agreement, Honda will provide vehicles from its fleet of electrified vehicles as the official transportation at the WCH Tokyo 25, which will start on September 13, 2025. This is the first time Honda has partnered with World Athletics. World Athletics President Sebastian Coe and Honda Global CEO Toshihiro MibeThe World Athletics Championships is the world’s premier track-and-field competition, with athletes from more than 200 countries and territories set to participate. WCH Tokyo 25 will be held at the National Stadium in Tokyo, Japan for nine days from September 13-21, 2025. This will be the third WCH to be held in Japan, and the second in Tokyo, who hosted the event 34 years ago, in 1991. By providing its fleet of electrified vehicles as part of the official competition transportation service, Honda will contribute to the sustainability objectives of WCH Tokyo 25. The official vehicles will be used for a variety of purposes, including leading the marathon races, driving referees, and moving officials and athletes involved in the event.Based on Honda’s vision for its sports activities which is “To increase the number of people who take on challenges through sports activities and make the lives of all people more enjoyable” – the company has been operating official club Honda teams -- including a track & field team -- sponsoring various athletics events and individual athletes. Through these activities, Honda has been and will continue to support various athletes who take on challenges toward the realisation of their own dreams.By sponsoring the WCH Tokyo 25, Honda is hoping to work with World Athletics and other partners to create the best international stage where track and field athletes from across the world can challenge their own limits and achieve their dreams.Comments by Toshihiro Mibe, Global CEO of Honda“We are honored to participate in the World Athletics Championships Tokyo 25 as a World Athletics Partner. Through environmentally-responsible Honda products and technologies, we will contribute to the reduction of the event’s environmental impact. Honda has a passion to support people who are taking on challenges toward their dreams, and to increase the number of people who are inspired and encouraged by seeing such challenges. Through the sponsorship of this event, we would like to convey such a passion of Honda to people around the world.”Comments by Sebastian Coe, World Athletics President“We are delighted to welcome Honda as the latest World Athletics global partner and have them on board for the World Athletics Championships Tokyo 25 – where they will provide electric vehicles as part of our common sustainability objectives. We are proud of this partnership as it brings together two organisations with a shared vision of creating a better future for generations to come. This giant of Japanese car manufacturing will support us to help minimise the environmental impact of our event and move closer to achieving a sustainable championships.”About HondaSince its foundation, Honda has been committed to "creating a society that is useful to people" by utilizing its technologies and ideas. We also focus on environmental responsiveness and traffic safety, and continue to take on the challenge of realizing a sustainable future. For more information, visit https://global.honda/en/.Head Office Contact Information: 2-1-1, Minami-Aoyama, Minato-ku, Tokyo 107-8556, JapanTel: +81-(0)3-3423-1111 (main) Copyright 2024 JCN Newswire via SeaPRwire.com.

Fujitsu Limited, Okinawa Cellular Telephone Company and Tokyo Marine Asset Management Co., Ltd., in collaboration with Eco Tour Fukumimi, and Nosoko Elementary School, have been engaged in a conservation project to regenerate the umishobu (Enhalus acoroides) seagrass bed in the Nosoko area of Ishigaki City, Okinawa Prefecture. This area has now been designated as Okinawa Prefecture's first Nationally Certified Sustainably Managed Natural Site (1), awarded by Japan's Ministry of the Environment.Project siteThe following characteristics of the project were key to the designation:1. Nosokozaki is the only area in Ishigaki Island where umishobu seagrass grows, making it a habitat for rare species. Until around 2010, before damage caused by sea turtles became serious, the area also supported a total of ten species of seagrass, providing water purification and blue carbon storage functions. If successful, these conservation efforts are expected to lead to the recovery of a comparable number of biomass and species.2. The project includes biodiversity conservation activities with Nosoko Elementary School students. This fosters biodiversity education, cultivates a culture of environmental stewardship, and strengthens the connection of future generations with nature.3. Umishobu seagrass stores carbon, contributing to decarbonization efforts. The amount of greenhouse gases (GHGs) stored by the umishobu will be measured and applied for as J Blue Credits (2).The area will also be registered in the international database as an OECM (3), contributing to the achievement of the international 30by30 (4) target.Fujitsu, Okinawa Cellular, and Tokyo Marine AM will continue to work together with the local community to contribute to the conservation and restoration of biodiversity.(1) Nationally Certified Sustainably Managed Natural Site :An area designated by Japan’s Ministry of Environment where biodiversity conservation is achieved through private sector initiatives.(2) J Blue Credits :Unique credits which are certified, issued, and managed by the Japan Blue Economy Association (JBE), following review and feedback from an independent third-party committee.(3) OECM (Other Effective area-based Conservation Measures) :Areas outside protected areas that contribute to biodiversity conservation.(4) 30by30 :One of the 2030 targets of the Kunming-Montreal Global Biodiversity Framework adopted at COP15, aiming to effectively conserve at least 30% of land and sea areas as healthy ecosystems by 2030.About FujitsuFujitsu’s purpose is to make the world more sustainable by building trust in society through innovation. As the digital transformation partner of choice for customers in over 100 countries, our 124,000 employees work to resolve some of the greatest challenges facing humanity. Our range of services and solutions draw on five key technologies: Computing, Networks, AI, Data & Security, and Converging Technologies, which we bring together to deliver sustainability transformation. Fujitsu Limited (TSE:6702) reported consolidated revenues of 3.7 trillion yen (US$26 billion) for the fiscal year ended March 31, 2024 and remains the top digital services company in Japan by market share. Find out more: www.fujitsu.com.Press ContactsFujitsu LimitedPublic and Investor Relations DivisionInquiriesOkinawa Cellular Telephone CompanySustainability Management Promotion Department, TsukayamaTEL: 098-951-0639Tokyo Marine Asset ManagementOkadaTEL: 03-3212-8301 Copyright 2024 JCN Newswire via SeaPRwire.com.

TOKYO, Nov 7, 2024 - (JCN Newswire via SeaPRwire.com) - Utilizing proprietary generative AI technology, NEC Bio has successfully modified T cell receptors (TCRs) to increase their efficacy. This achievement marks a major step forward in drug development and personalized medicine since prediction and engineering of TCR sequences that are able to bind to specific target sequences remains a major challenge in the field. The technology is being presented as a poster at the 39th Annual Meeting of the Society for Immunotherapy of Cancer (SITC) in Houston, Texas, from November 6 to 10, 2024.Advancing Personalized Cancer TreatmentNEC Bio’s mission is to develop groundbreaking therapies for patients around the globe using advanced cutting edge AI technologies. TCR-based therapies use the high binding affinity of TCR to bind to defined cancer cells and destruct them using various strategies. One major hurdle in the development of TCR therapies is the difficulty in identifying TCR sequences that will bind specifically to given target sequences. Conventionally, this involves a labor-intensive process of lab screening, trying to isolate the necessary TCR from human donor cells.Motoo Nishihara, Corporate Executive Vice President and CTO of NEC, said: "We are incredibly proud to announce our work on T Cell Receptor engineering using our proprietary generative AI, presented at the Society for Immunotherapy of Cancer annual meeting. This initiative emphasizes our dedication to advancing immunotherapy and highlights the transformative potential of our technology. We are excited about the future and the significant impact our innovations will have on the field of cancer treatment. This technology makes our portfolio stronger and serves our mission to bring AI-led innovative medicine to patients globally."About the technologyThe AI model developed at NEC Bio utilizes generative AI and domain-specific large language models (LLMs) for creating novel TCRs with high efficacy. Given a target peptide, the AI model can generate high affinity TCR sequences for targeted therapy based on knowledge from machine learning on physio-chemical TCR interactions. The AI was benchmarked on public datasets and achieved better performance than baseline methods. The AI-designed TCRs were shown to have enhanced TCR activities in cell-based assays conducted in collaboration with Aichi Cancer Center.Building on this success, NEC Bio will expand the application of its generative AI technology to design TCRs for various oncodriver targets, antibodies for specific targets, immunoproteins, DNA constructs, mRNA constructs, and more. This broad application spectrum highlights NEC Bio’s commitment to pushing the boundaries of what is possible in drug design and development.SITC poster detailsNEC Bio is presenting this technology in a poster at the Society for Immunotherapy of Cancer (SITC), in Houston, Texas, from November 6 to 10, 2024. Details on the poster are below:Poster title: Design of Enhanced TCRs Against Cancer Antigens Using an AI SystemAuthors: Martin Renqiang Min, Tianxiao Li, Kazuhide Onoguchi, Daiki Mori, Jonathan Warrell, Pierre Machart, Anja Moesch, Andrea Meiser, Ivy Grace Pait, Ayako Okamura, Daisuke Muraoka, Hirokazu Matsushita, Kaidre BendjamaPoster Number: 1230Date: November 7, 2024The poster can be found here: Home | NEC Bio B.VAbout NEC CorporationNEC Corporation has established itself as a leader in the integration of IT and network technologies while promoting the brand statement of “Orchestrating a brighter world.” NEC enables businesses and communities to adapt to rapid changes taking place in both society and the market as it provides for the social values of safety, security, fairness and efficiency to promote a more sustainable world where everyone has the chance to reach their full potential.For more information, visit NEC at https://www.nec.com.About NEC BioNEC Bio, the biotech arm of NEC Corporation, is based in the Netherlands and dedicated to the development of innovative biotechnological solutions to tackle some of the most pressing health challenges. NEC Bio's research and development efforts are focused on creating personalized therapies that improve the quality of life for patients worldwide. NEC OncoImmunity in Oslo, Norway, is also a subsidiary of NEC Bio. For more information, visit Home | NEC Bio B.V (nec-bio.com)Media contact:7-1, Shiba 5-chome,Minato-ku, Tokyo 108-8001, JapanPhone: +81-3-3454-1111 Copyright 2024 JCN Newswire via SeaPRwire.com.

TOKYO, Nov 7, 2024 - (JCN Newswire via SeaPRwire.com) - Anime Tokyo Station, an anime exhibition hub that utilizes Japanese anime content with a strong fan base around the world and is operated by The Association of Japanese Animations, is celebrating its one-year anniversary since its opening last October. A ceremony and entertainment-filled event was held on October 31 to commemorate the first anniversary.At the 1st Anniversary Event, congratulatory remarks were received from Tokyo Governor Yuriko Koike and Toshima City Mayor Miyuki Takagiwa. The event was hosted by popular voice actors Miina Tominaga and Ryusei Nakao, and featured a congratulatory video message from Masako Nozawa, marking her first appearance since the grand opening. In addition, characters Anpanman, Baikinman, and Dokin-chan from “Sore Ike! Anpanman,” in which Tominaga and Nakao do character voices, also made special appearances as greeting characters, adding to the excitement.In the second half of the event, Tominaga and Nakao performed a dramatic reading of the first volume of Arashi no Yoru ni,” a popular picture book in Japan. Accompanied by percussion-based music, the reading created an immersive atmosphere. As a surprise guest, Yuichi Kimura, the original author of Arashi no Yoru ni, appeared on stage, sharing his impressions of the reading and stories about his favorite anime from childhood in a talk session. This 1st Anniversary Event at Anime Tokyo Station offered a unique entertainment experience, captivating eyes and ears with many attractive aspects of anime.Anime Tokyo Station preserves approximately 50,000 valuable materials related to past anime production processes. The facility serves as a launch point into the world of anime, where a variety of people such as travelers visiting Tokyo from all over the world can gather and enjoy discovering both past masterpieces and the latest popular series, thereby sharing the appeal of anime and Tokyo to a wide range of anime fans both in Japan and overseas.Overview of the Facility- Name: Anime Tokyo Station (abbreviation: Anime Tokyo)- Location: Tokyu Building East Building No.5, 1-2F above ground, B1F below ground (2-25-5, Minami-Ikebukuro, Toshima Ward, Tokyo) *4-minute walk from Ikebukuro Station- Hours: 11:00 a.m. - 7:00 p.m. (last admission by 6:45 p.m.)- Closed: Mondays *If Monday is a holiday, the museum will be open on Monday and closed the following day. Also closed on New Year holidays, temporary closures, etc. *Please check the official website before visiting.- Admission: Free- Official website: https://animetokyo.jp/en/Press release: https://www.acnnewswire.com/docs/files/20241106.pdf  Copyright 2024 JCN Newswire via SeaPRwire.com.

SAN FRANCISCO, CA & MUMBAI, Nov 6, 2024 - (ACN Newswire via SeaPRwire.com) - CleverTap, the all-in-one engagement platform, today released its latest Market Research Report with insights into the global banking landscape, “Banking on AI: A Leader's Guide to Customer Engagement Excellence in Banking”. The report reveals that 57% of banking executives have yet to achieve a unified customer view, indicating significant challenges with data silos due to technological barriers and cost constraints. These data challenges are impacting banks’ ability to deliver personalized, seamless customer experiences in an era where AI-driven engagement is becoming essential.The research explores the transformative shift within the banking sector leveraging AI to address modern banking challenges, including the need for personalized and secure digital experiences amid rapid digital transformation. Through this study, CleverTap set out to identify where the AI opportunity lies for banks and introduced its strategic framework to help banks build excellence in customer engagement, along with highlighting key trends for Banks in customer engagement within the AI space, while understanding the challenges and opportunities faced by banking leaders. Furthermore, the company also assessed AI's role in enhancing customer experiences.The methodology included a survey of 50 senior executives in India’s banking sector, in-depth interviews for qualitative insights, and analysis of industry benchmarks and best practices. This research covered banks with a combined total asset size of about $3.03 trillion, spanning APAC, the Middle East, North America, LATAM, and the EU.Insights from the report reveal that 3 out of 4 banking executives may be missing out on critical opportunities to build customer loyalty and drive sustainable growth, as they focus heavily on short-term revenue targets. To effectively balance short-term metrics with long-term financial outcomes, banks need to harness advanced analytics that not only track current performance but also predict future customer behaviors.To assess the gaps and identify opportunities for the banking sectors in the age of AI, CleverTap has developed a framework that will serve as a foundation to improve customer experiences and drive long-term value. CleverTap’s Core Four Framework – encompassing Trust, Technology, Touchpoints, and Transactions – is designed to help banks transition from product-focused to customer-centric approaches, cultivating deeper relationships and delivering phy-gital experiences. The research covers the nuances for retail banks, neo-banks, and specialized banks, providing insights across the four core pillars.Key gaps identified basis of the framework include:Loyal customers generate 2.5x higher transaction value than others, and referred prospects are 3.5x more likely to onboard. However, 50% of banking executives do not effectively leverage their high-NPS (Net Promoter Score) customers57% of banking executives have yet to implement a unified customer view, suggesting issues with data silos. The primary obstacles to unification are technological challenges and associated costs41% of banking executives are not using real-time segmentation capabilities, limiting their ability to deliver timely and personalized communicationBanks using more than four channels in their engagement campaigns see a 53% improvement in conversions compared to those using fewer than four channels, yet only about 33% of banks have adopted this approachBanks can harness the power of the Core Four by implementing a comprehensive AI strategy, as detailed in CleverTap’s report Banking on AI: A Leader's Guide to Customer Engagement Excellence in Banking.This approach consists of three key stages:Operational Optimizers focus on using AI to enhance operational efficiency through the automation of routine tasks and improved workflow processesPersonalization & Experimentation Architects where AI is applied to improve orchestration while personalizing interactions and conducting experiments at scale to boost conversionStrategic Innovators showcase the use of AI for automating strategic decision-making and providing deeper insights for long-term planningCommenting on the report, Jacob Joseph, VP - Data Science, CleverTap said, “The banking sector has often played catch-up when it comes to tech innovations, but customer familiarity with digital solutions is making it clear that banks need to bridge this divide quickly. The banking sector often remains a 'follower' in tech adoption. This cautious stance means banks typically wait for proof of concept before fully embracing new technologies. Our latest report dives into how AI can bridge the current gaps in customer experience and operational efficiency, helping banks not only meet evolving customer expectations but exceed them. By deploying integrated, AI-powered solutions, banks can deliver the hyper-personalized experiences today’s customers expect, building lasting trust and loyalty. For banks aiming to stay competitive in a digital-first world, AI isn’t optional - it’s essential.”Looking ahead at the future of the banking sector with AI, CleverTap’s latest insights highlight six transformative AI outlooks that are poised to redefine customer engagement and operations:Customer engagement for banking is driven by innovations like synthetic data, which enhances analytics without compromising privacyBanks are also prioritizing emotional engagement, using AI to create immersive experiences and personalized gamification that fosters customer loyaltyModernizing MarTech through AI-powered ecosystems allows banks to integrate data and services seamlessly, enhancing customer experiencesA shift towards a customer-centric approach, leveraging AI for dynamic personalization, further strengthens relationships and retentionAdditionally, implementing responsible AI frameworks builds trust by ensuring transparency  and complianceFinally, the collaboration with fintech firms through AI-powered open banking creates holistic financial ecosystems, offering a wider range of services and real-time insights to customers, thereby increasing trust and engagementFor more information and insights download the report here.About CleverTapCleverTap is the leading all-in-one customer engagement platform that helps brands unlock limitless customer lifetime value. CleverTap is trusted by over 2000 brands like Domino’s, Levis, Jio, Papa John’s, Zomato, Kotak Bank, Air Asia, Carousell, TD Bank, and Tesco to help build personalized experiences for all their customers. The platform is powered by TesseractDB™ – the world’s first purpose-built database for customer engagement, offering speed and cost efficiency at scale.Backed by top-tier investors such as Accel, Peak XV Partners, Tiger Global, CDPQ, and 360 One, the company is headquartered in San Francisco, with presence across Seattle, London, São Paulo, Bogota, Mexico, Amsterdam, Sofia, Dubai, Mumbai, Bangalore, Singapore, Vietnam, and Jakarta.For more information, visit clevertap.com or follow us on:LinkedIn: https://www.linkedin.com/company/clevertap/ X: https://twitter.com/CleverTap Forward-Looking StatementsSome of the statements in this press release may represent CleverTap's belief in connection with future events and may be forward-looking statements, or statements of future expectations based on currently available information. CleverTap cautions that such statements are naturally subject to risks and uncertainties that could result in the actual outcome being absolutely different from the results anticipated by the statements mentioned in the press release.Factors such as the development of general economic conditions affecting our business, future market conditions, our ability to maintain cost advantages, uncertainty with respect to earnings, corporate actions, client concentration, reduced demand, liability or damages in our service contracts, unusual catastrophic loss events, war, political instability, changes in government policies or laws, legal restrictions impacting our business, the impact of a pandemic, epidemic, any natural calamity and other factors that are naturally beyond our control, changes in the capital markets and other circumstances may cause the actual events or results to be materially different, from those anticipated by such statements. CleverTap does not make any representation or warranty, express or implied, as to the accuracy, completeness, or updated or revised status of such statements. Therefore, in no case whatsoever will CleverTap and its affiliate companies be liable to anyone for any decision made or action taken in conjunction.For more information:SONY SHETTYDirector, Communications, CleverTap+91 9820900036sony@clevertap.com ASHMIT CHAUDHARYAssociate Consultant, Archetype+91 8850752121ashmit.chaudhary@archetype.co  Copyright 2024 JCN Newswire via SeaPRwire.com.

Milan, Italy, Nov 6, 2024 - (JCN Newswire via SeaPRwire.com) - Honda has unveiled two electric motorcycle concept models, the “EV Fun Concept” and the “EV Urban Concept,” at EICMA 2024 in Milan, Italy (Press days: November 5-6, Public days: November 7-10).Honda world-premiered two concept models, the EV Fun Concept and the EV Urban Concept, at EICMA 2024.The EV Fun Concept is Honda’s first electric sports model and is scheduled to go on sale in 2025.The EV Urban Concept embodies Honda’s vision of urban mobility in the near future.Beyond 2025, Honda aims to increase the variety of its electric line-up with the aim of becoming the leading company for electric motorcycles.Honda aims to achieve carbon neutrality through all of its products and corporate activities by 2050, and in particular, achieve carbon neutrality for all of its motorcycle products in the 2040s. Toward this goal, Honda is working to electrify its motorcycles as the mainstay of its future environmental strategy.Honda has positioned 2024 as the first year for the global launch of its electric motorcycles and has begun full-scale entry into the electric motorcycle market, positioning the time up to 2026 as a period of market entry, and beyond 2026 as a period of business expansion.The EV Fun Concept is an electric motorcycle designed for fun use and was referred to at its “2023 Briefing on Honda Electric Motorcycle Business” meeting held on November 29, 2023. The EV Fun Concept is a naked sports model equivalent to a mid-sized internal combustion engine (ICE) motorcycle. It is Honda’s first electric sports model to be equipped with a fixed battery and is scheduled to be commercialized in 2025.The EV Urban Concept is an electric model that embodies Honda’s vision of urban electric mobility with its function-focused design, connected technologies, and in-house developed battery pack.With the addition of the new sports EV Fun Concept, and the EV Urban Concept-, Honda is making solid progress toward its plan to introduce 30 electric models globally by 2030.Honda will accelerate its efforts to develop a full lineup of electric motorcycles to meet the diversifying needs of customers and promote the development of a wide variety of electric vehicles. Through its efforts, Honda aims to expand its global market share and become the leading company also in the field of electric motorcycles.EV Fun ConceptThe EV Fun Concept is Honda’s first electric sports model and is being developed as a next-generation electric motorcycle that offers a new sensation of quiet riding and an emotional feeling unique to electric motorcycles.In addition to the high level of “riding, turning, and stopping” created by Honda’s long-developed motorcycle technologies, the new quiet, vibration-free ride that is only possible with electric power and the slim, easy-to-manage chassis package realized by its fixed battery will provide a new emotional experience that is very different to ICE motorcycles. Honda believes the new electric experience will enhance customers’ motorcycle lifestyles.The EV Fun Concept’s system and charging were developed by applying Honda’s know-how and technologies cultivated in its automobiles and power products. The battery is compatible with the CCS2* quick charger, the same standard as automobiles, and has been developed to optimize the balance between light weight and quick charging performance, as well as to provide a cruising range of over 100km or more, sufficient for city use.*CCS2: Combined Charging System Type 2, a specification for EV quick charging connectorsThe EV Urban Concept reconstructs from scratch Honda’s vision of what urban electric mobility should be. It embodies a vision of near-future mobility that cooperates and resonates with people and society through its essential and sophisticated styling, intuitive human-machine interface (HMI), and new experiences created by the fusion of software and hardware. Honda’s goal is to open up the freedom of mobility to as many customers as possible, and to expand the possibilities of mobility for each and every customer.Honda Motor Europe Limited, Honda’s UK subsidiary, has released details on the EV Fun Concept and EV Urban Concept on its website.Video site:URL: https://www.youtube.com/watch?v=v8hzcn4so7sAbout HondaSince its foundation, Honda has been committed to "creating a society that is useful to people" by utilizing its technologies and ideas. We also focus on environmental responsiveness and traffic safety, and continue to take on the challenge of realizing a sustainable future. For more information, visit https://global.honda/en/.Head Office Contact Information: 2-1-1, Minami-Aoyama, Minato-ku, Tokyo 107-8556, JapanTel: +81-(0)3-3423-1111 (main) Copyright 2024 JCN Newswire via SeaPRwire.com.

Yoshimoto Kogyo Holdings Co., Ltd. (hereinafter referred to as Yoshimoto Kogyo) and Mitsubishi Corporation have agreed to consider business co-creation, including solving consumers' health issues through “laughter”, overseas development of “comedy content”, and content production using digital transformation, and have concluded a business partnership agreement.With the advent of a super-aged society in Japan, there is a renewed focus on the health benefits of laughter, as people seek to prevent dementia and brain aging, and achieve well-being. Yoshimoto Kogyo and MC will work together to solve the health issues faced by consumers through laughter and health care. In addition, MC intends to widely promote Japan's excellent intangible assets as brands in the overseas markets and will jointly deliver Yoshimoto Kogyo's Japanese comedy content as an attractive intangible asset to the rest of the world. The companies will utilize MC's digital transformation expertise to capture and monitor consumer health data and to produce comedy content, aiming to co-create new added value through the combination of comedy and digital technology.Based on this agreement, Yoshimoto Kogyo will be responsible for the planning and production of content and collaborative goods that it has cultivated through its business to date, while MC will utilize its human resources and networks both in Japan and overseas, its business expertise in digital and health care, and its manufacturing and sales network for retail and miscellaneous goods. In addition, the two companies will aim to create new businesses through the exchange of human resources.Specifically, the companies will begin joint discussions on (1) new services based on solving health issues through laughter, (2) joint production and distribution of new content utilizing digital technology, (3) overseas development of comedy content, (4) regional revitalization utilizing the business platforms of both groups, (5) production and sales of merchandise, and (6) other new services.Through this initiative, Yoshimoto Kogyo and MC aim to provide “Smart Life,” a healthier and better lifestyle, to people around the world.About Yoshimoto Kogyo Holdings Co., Ltd.Head office: 11-6 Sennichimae, Namba, Chuo-ku, OsakaRepresentative: Akihiko Okamoto, President and Chief Executive OfficerEstablished: 1912Business description: Theater operation, talent agency, production and sales of video and other content, other businessesAbout Mitsubishi CorporationHead office: 3-1, Marunouchi 2-Chome, Chiyoda-ku, TokyoRepresentative: Katsuya Nakanishi, Representative Director, President and CEOEstablished: 1954Business description: The company develops diversified businesses in a wide range of industries through its eight groups: Environmental Energy, Materials Solution, Mineral Resources, Urban Development & Infrastructure, Mobility, Food Industry, S.L.C. (Smart-Life Creation), and Power SolutionInquiry RecipientMitsubishi CorporationTelephone: +81-3-3210-2171 Copyright 2024 JCN Newswire via SeaPRwire.com.

TOKYO, Nov 6, 2024 - (JCN Newswire via SeaPRwire.com) - Honda Motor Co., Ltd. (Honda) and GoCimo (formerly known as GoCiklo) (CEO: Mattias Tingvall), a Swedish start-up that operates rental and sharing service of electric motorcycles with swappable batteries, will together commence a battery sharing service verification test in Malmö, Sweden in February 2025 for a period of one year.The purpose of the test is to verify the acceptability of a battery sharing service in Europe, the suitability of a new battery swap station, and the business feasibility of the service.The test will consist of Honda Power Pack Exchanger e: (battery swap station), located at three locations in Malmö, to be used to exchange Honda Mobile Power Pack e: (batteries) for the EM1 e: (electric scooter commuter) sold by Honda in Europe. For this test, Honda will provide hardware and systems, including 30 pcs of EM1 e:, 60 pcs of Honda Mobile Power Pack e, and three Honda Power Pack Exchanger e:, as well as after-sales service.GoCimo was established in 2022 to address rising emissions and traffic congestion in the delivery and transportation industries, driven by the growth of the urban logistics market. So far, GoCimo has operated battery sharing services in two Swedish cities (Stockholm and Gothenburg). In this verification test, GoCimo will be responsible for the operation of the battery sharing service, customer acquisition and management, and securing locations for battery exchange stations.Honda and GoCimo will also evaluate the potential for a long-term partnership for the European market during the verification test.Honda has already launched battery sharing services in Japan, India, Indonesia, and Thailand. This verification test in Sweden will mark the fifth country for Honda’s battery sharing services.Beginning with this initiative with GoCimo, Honda aims to promote the electrification of motorcycles and the widespread use of swappable batteries in Europe by expanding battery sharing services using Honda products, mainly for business users, in major European cities, thus supporting the electrification of mobility and contributing to the realization of a low-carbon society.Daiki Mihara : Operating Executive, MCPP Elect Biz Dev Unit, Honda Motor Co., Ltd.“Honda is promoting the spread of electric motorcycles globally. The joint verification test of the battery sharing service with GoCimo will create a new business model for electric motorcycles in Europe, which will be commercialized and rolled out across the entire European region in the future to accelerate the spread of electric motorcycles and Honda Mobile Power Pack e:.”Mattias Tingvall : CEO GoCimo“GoCimo has successfully validated the business model for battery-sharing subscriptions for light vehicles in Europe. Our customers confirm that our service helps them transition to electric vehicles by lowering the investment hurdle, minimizing downtime due to charging, and improving safety during the charging process. This joint verification test with Honda allows us to further explore the market potential of battery-sharing services.”About HondaSince its foundation, Honda has been committed to "creating a society that is useful to people" by utilizing its technologies and ideas. We also focus on environmental responsiveness and traffic safety, and continue to take on the challenge of realizing a sustainable future. For more information, visit https://global.honda/en/.Head Office Contact Information: 2-1-1, Minami-Aoyama, Minato-ku, Tokyo 107-8556, JapanTel: +81-(0)3-3423-1111 (main) Copyright 2024 JCN Newswire via SeaPRwire.com.

MILAN, Nov 6, 2024 - (JCN Newswire via SeaPRwire.com) - Honda unveiled the world’s first* V3 motorcycle engine with an electrical compressor, at EICMA 2024 (the Milan Motorcycle Shows; Press days: November 5-6, Public days: November 7-10) in Milan, Italy.The water-cooled 75-degree V3 engine is being newly developed for larger displacement motorcycles, and has been designed to be extremely slim and compact. It features the world’s first electrical compressor for motorcycles, which is able to control compression of the intake air irrespective of engine rpm, meaning that high-response torque can be delivered even from lower rpm. In addition, the electrical compressor allows a high degree of freedom of layout of all components in the limited space available on a motorcycle and efficient centralization of mass. It also does not require any form of intercooler.  Honda’s motorcycle business aims to provide products that meet the needs of various customers by offering a wide range of products from commuters to FUN models. In addition, Honda is taking on the challenge of developing advanced technologies by adding electric motorcycles and other products to its product lineup to meet the diversifying needs of today’s customers.Honda sees the development of this V3 engine with an electrical compressor as a new challenge in the area of internal combustion engines, and its goal is to enable customers to further experience the joy of riding and owning a motorcycle. Honda plans to apply the new V3 engine to larger displacement models in the future, and will continue its development toward mass production.*Honda researchAbout HondaSince its foundation, Honda has been committed to "creating a society that is useful to people" by utilizing its technologies and ideas. We also focus on environmental responsiveness and traffic safety, and continue to take on the challenge of realizing a sustainable future. For more information, visit https://global.honda/en/.Head Office Contact Information: 2-1-1, Minami-Aoyama, Minato-ku, Tokyo 107-8556, JapanTel: +81-(0)3-3423-1111 (main) Copyright 2024 JCN Newswire via SeaPRwire.com.

Toyota City, Japan, Nov 5, 2024 - (JCN Newswire via SeaPRwire.com) - TOYOTA GAZOO Racing completed a thrilling fightback to overcome challenges and retain its FIA World Endurance Championship (WEC) title when the 2024 season came to a dramatic conclusion in the 8 Hours of Bahrain.Starting from one-two on the grid, and knowing a win would secure the manufacturers’ title, each car led at different points, but the team entered the final stages of the race with only one car on track, down in 10th place after suffering setbacks.An incredible team effort and a dominant driving display saw Sébastien Buemi cut through the field to win the race in the #8 GR010 HYBRID he shares with Brendon Hartley and Ryo Hirakawa, securing the team’s sixth successive manufacturers’ World Championship, by six points from Porsche.The #7 GR010 HYBRID had victory in its sights when it led at half distance, but a fuel pump issue forced Mike Conway, Kamui Kobayashi and Nyck de Vries into retirement. That ended the slim drivers’ title hopes of Kamui and Nyck, who needed a win to have any chance.The chequered flag in Bahrain concluded a 2024 season which featured 72 hours of racing, at eight rounds on four continents over almost 10 months. TOYOTA GAZOO Racing’s season record stands at five podiums, including three wins, and two pole positions, earning 190 World Championship points. After an exciting year, TOYOTA GAZOO Racing congratulates new drivers’ World Champions Kévin Estre, Andre Lotterer and Laurens Vanthoor, and thanks all WEC competitors for their contribution to a memorable season.A dramatic and challenging race had started strongly for the team when Sébastien led away from pole. But after 18 minutes its hopes suffered a blow when Sébastien was hit from behind by a GT car and spun down to seventh. He recovered to fifth before Brendon took over late in the second hour.Brendon and Ryo then battled against tyre degradation on their stints but made a determined effort to keep the #8 in the top six and still in the hunt. The race turned on two safety car periods early in the second half of the race, which closed the gaps throughout the 18-strong Hypercar field.When racing resumed with just over an hour remaining, Sébastien was 10th but only 15secs from the lead, and he began an incredible fight back to revive the team’s World Championship dream. A heroic charge through the field saw him overtake several rivals to move into second after his final pit stop.With just over half an hour of the season remaining Sébastien completed a remarkable comeback drive by passing the #5 Porsche for the lead. He soon established a comfortable advantage and reached the chequered flag to win by 27.539secs for the #8 GR010 HYBRID’s second win of the season, and the team’s 10th in Bahrain.For much of the race, the #7 car had looked the most likely GR010 HYBRID to challenge for victory. Mike moved up from fourth at the end of the first lap to be in the top three when Kamui took the wheel for what would be a dramatic stint. As the sun set in the fourth hour, Kamui’s bold overtaking elevated him to second.However, the #7 was hit by a fuel pump issue which intermittently reduced performance. Drivers, engineers and mechanics looked for a solution and, initially, appeared to have succeeded when Kamui closed the gap and Nyck took the lead via a fast pit stop. But the trouble returned and the #7 slipped down the field.Considering the problem would require a lengthy repair, the team prioritised victory and the championship. It decided to retire the #7 with just over two hours to go, in order to allow its crew members to support the #8 car’s challenge, expressing their solidarity and ensuring today’s title triumph was a genuine team effort.Kamui Kobayashi (Team Principal and driver, car #7):“First of all, a big thank you for all the support we have had this season from all over the world. Winning the manufacturers’ World Championship is a great achievement and it’s the result of a huge team effort from everyone, including our Toyota colleagues and our partners, who are a big part of this success. This is the result everyone in the team wanted and they gave everything to achieve it, so thank you for all that work. Car #8 deserved the win today after an incredible race. Obviously on our car we had some issues and had to retire. We will analyse that and aim to come back even stronger next season.”Mike Conway (Driver, car #7):“It was obviously a disappointing outcome for our car. We were very strong at some points and looking good to win, then we ran into the issue which unfortunately took us out of the race. But at least car #8 won and that means we achieved our target of winning the manufacturers’ World Championship. I am very happy for the team and for Toyota, and I’m also pleased for car #8 to win the race with such a strong drive at the end. We’ll all enjoy this moment.”Nyck de Vries (Driver, car #7):“It’s great to end the season on a high for the team by winning the manufacturers’ World Championship with an amazing victory for car #8. Obviously, it’s bittersweet for our car to see our title rivals not score any points, considering we were in a winning position. Without the technical issue we had the chance to win both championships but that’s part of the game and we have to take it on the chin. Overall, I am just so happy for the team to get their reward today because they really deserve it after an eventful and challenging season.”Sébastien Buemi (Driver, car #8):“It’s crazy to think we won the race considering how it was going at some point. Against all the odds, with issues, penalties and bad luck it’s an amazing feeling for the team to win the World Championship. That was our target here and we’ve achieved it thanks to a brilliant effort from the team. When our car was down in 10th, we were going to the back of the Hypercar field during the pit stops and I thought we were done. But my team-mates did a good job hanging on with the old tyres and that meant I had a tyre advantage at the end. When it mattered today, we did a good job together and I am so pleased for the whole team.”Brendon Hartley (Driver, car #8):“I am so happy for everyone in the team and at Toyota. The race didn’t go as smoothly at the beginning as it could have done. We tried the medium tyres, but it didn’t work. Then at the end Séb did an unbelievable stint. He was the star; it was an incredible drive. Thanks to everyone in the team, at Toyota and all our partners. We really had to fight for this win and championship, so it means a lot. For our car to end the season with a victory is fantastic going into the winter break.”Ryo Hirakawa (Driver, car #8):“What a day. It was an up and down race, but we never gave up and we fought as one team. We started from pole, then got hit by a GT car but still tried our best and put everything behind Séb for a maximum push at the end. On the #8 car, we have had some difficulties this season, so I am happy to finally get a bit of luck. It’s fantastic to finish the season with a win and I am so grateful to the team, as well as to everyone at Toyota and all our partners, for their big efforts to win this manufacturers’ championship.”8 Hours of Bahrain – Result1st #8 TOYOTA GAZOO Racing 235 laps2nd #51 Ferrari AF Corse (Pier Guidi/Calado/Giovinazzi) +27.539secs3rd #5 Porsche Penske (Campbell/Christensen/Makowiecki) +29.177secs4th #93 Peugeot TotalEnergies (Jensen/Müller/Vergne) +36.799secs5th #35 Alpine Endurance Team (Chatin/Habsburg/Gounon) +37.404secs6th #15 BMW M Team WRT (Vanthoor/Marciello/Wittmann) +47.916secsDNF #7 TOYOTA GAZOO Racing Copyright 2024 JCN Newswire via SeaPRwire.com.

TOKYO, Nov 5, 2024 - (JCN Newswire via SeaPRwire.com) - Tokyo Stock Exchange, Inc. (TSE) and Fujitsu Limited today announced the successful renewal and operational launch of the TSE's cash equity trading system "arrowhead4.0." This renewal signifies the fourth generation of arrowhead, which originally commenced operations in January 2010.1. Key pointsIn this renewal, several measures have been implemented to enhance market convenience, including an introduction of the closing auction session, a new service that distributes market information by each order, and a bulk order cancellation function for users such as institutional investors. Additionally, to maximize trading opportunities for investors and other users, trading hours have been extended and resilience has been strengthened.(1) Improving Market Convenience- Introduction of the Closing Auction SessionConsidering the increasing importance of trading at close, and with the aim of further enhancing transparency in the formation of closing prices, this iteration of arrowhead introduces a closing auction session. This session provides a five-minute order acceptance period from 3:25 p.m. in the afternoon session, followed by a closing auction at 3:30 p.m. At the closing auction, even if orders do not match according to the previous rules, they can be executed at the upper or lower limits of the executable price range if certain conditions are met, thereby improving the opportunity for the formation of closing prices (Special Execution).- Market Information Service formed as a Market by OrderMarket by Order service, which distributes market information for each order, has been launched. This new service allows users to obtain more detailed market information for each order, in addition to the aggregated market information by price that has been available up to now.- Mass CancellationTo enhance convenience for users such as institutional investors, a function has been equipped that allows the cancellation of multiple orders in bulk on a user-by-user basis.(2) Maximizing Trading Opportunities- Extension of Trading HoursIn order to maximize trading opportunities for investors and improve the convenience of the market, the closing time of TSE has been extended by 30 minutes from 3:00 p.m. to 3:30 p.m.- Enhancement of ResilienceBy triplicating trading data in memory and operating multiple servers in parallel, it is now possible to switch servers in seconds and to ensure data integrity in the event of system failures, thereby realizing safe and secure system operation. In preparation for system failures, it continues to make improvements to ensure the continuation of trading. It will also be able to ensure trading opportunities through efforts to recover the system more quickly and smoothly than ever before.2. The Highly Reliable Technology and Support behind “arrowhead4.0”System reliability and processing performance have been improved by combining Fujitsu’s latest products, including reliable and high-performance servers, and middleware incorporating new high-speed technologies, with the know-how and technical capabilities of engineers who have built systems over many years.Based on the high-quality system development process that has been built and improved through arrowhead project in the past, the following efforts have been made to further enhance reliability and stability and improve resilience.(1) Introduction of Resilience Improvement FunctionsWith Fujitsu Software Primesoft Server, ultra high-speed in-memory data management software that combines high reliability and scalability, transaction data is placed in memory to achieve high response performance from ultra high-speed data access at the microsecond (one millionth of a second) level and throughput performance is achieved by placing transaction information in memory.Furthermore, product improvements have been made to shorten failure recovery time with system reboots. In addition, a monitoring dashboard was constructed to visualize the normality of the services provided by arrowhead4.0.(2) Improvement of System Performance and ToleranceBy upgrading the infrastructure to 462 PRIMERGY RX2540 M6 (1) servers, the latest high-performance and high-reliability x86 servers from the Fujitsu Group, system performance, including capacity and throughput, has been improved, and tolerance has been enhanced.(3) Promotion of “loosely-coupled” systemsThe system log data storage for business analysis was separated from the trading core function, and built on a cloud computing platform provided by Japan Exchange Group, Inc. By loosely coupling some of the functions of data analysis and trading on the system, the reliability of market operations was improved. In addition, more flexible market data analysis is now possible.(4) Advanced Failure ResponseTSE and Fujitsu have built a unified team to respond to system failures. In the case of a system failure, the team will work quickly to identify the cause of the failure and the scope of the impact.3. About the FutureTSE and Fujitsu will continue to further develop the market by responding to changes in the market environment and diversifying investor needs, further enhancing the convenience of market users and the international competitiveness and resilience of the Tokyo market, as well as realizing safe and secure trading on the market.TrademarksAll company or product names mentioned herein are registered trademarks of their companies.[1]“PRIMERGY RX2540 M6” :Fujitsu Group's x86 servers. The PRIMERGY brand was transferred to Fsas Technologies Inc. in April 2024.About Tokyo Stock Exchange, Inc. (TSE)Tokyo Stock Exchange is licensed as a financial instruments exchange under the Financial Instruments and Exchange Act and operates financial instruments markets.The market capitalization of companies listed on the Tokyo Stock Exchange is the third largest in the world and the largest in Asia, and we have established our position as the central market in Japanese securities.Tokyo Stock Exchange is a wholly owned subsidiary of Japan Exchange Group, Inc. (Code: 8697).About FujitsuFujitsu’s purpose is to make the world more sustainable by building trust in society through innovation. As the digital transformation partner of choice for customers in over 100 countries, our 124,000 employees work to resolve some of the greatest challenges facing humanity. Our range of services and solutions draw on five key technologies: Computing, Networks, AI, Data & Security, and Converging Technologies, which we bring together to deliver sustainability transformation. Fujitsu Limited (TSE:6702) reported consolidated revenues of 3.7 trillion yen (US$26 billion) for the fiscal year ended March 31, 2024 and remains the top digital services company in Japan by market share. Find out more: www.fujitsu.com.Press ContactsTokyo Stock Exchange, Inc. IT Development Department Trading SystemTEL:+81-3-3666-0141 (representative)Fujitsu LimitedPublic and Investor Relations DivisionInquiries Copyright 2024 JCN Newswire via SeaPRwire.com.

- Order intake grew YoY in Energy Systems, Plants & Infrastructure Systems, and Logistics, Thermal & Drive Systems segments due to contributions from GTCC and Aero Engines in Energy Systems and Metals Machinery in Plants & Infrastructure Systems.- Revenue increased YoY in Energy Systems, Plants & Infrastructure Systems, and Aircraft, Defense & Space segments. Revenue growth was especially large in Aircraft & Missile Systems within Defense & Space.- Business profit showed strong YoY growth in Energy Systems, Plants & Infrastructure Systems, and Aircraft, Defense & Space segments due to positive impact of revenue increases, margin improvements, and yen depreciation.- Increased full-year order intake guidance mainly due to continued strong demand in Energy Systems segment.TOKYO, Nov 5, 2024 - (JCN Newswire via SeaPRwire.com) - Mitsubishi Heavy Industries, Ltd. (MHI, TSE Code: 7011) announced that order intake rose 7.9% year-on-year to ¥3,383.5 billion in the half year ended September 30, 2024. Revenue rose 11.1% to ¥2,298.1 billion year-on-year, resulting in profit from business activities (business profit) of ¥188.4 billion, an 86.7% increase over the previous fiscal year, which represents a profit margin of 8.2%. Profit attributable to owners of parent (net income) was ¥107.1 billion, an increase of 16.5% year-on-year, with a profit margin of 4.7%. EBITDA was ¥266.2 billion, a 57.7% increase over 1H FY2023, with an EBITDA margin of 11.6%, up 3.4 percentage points year-on-year.(billion yen, except where otherwise stated)1H FY2024 Financial Results1H FY20231H FY2024YoYYoY%Order Intake3,137.03,383.5+246.4+7.9%Revenue2,069.22,298.1+228.8+11.1%Profit from Business ActivitiesProfit Margin100.94.9%188.48.2%+87.4+3.3 pts+86.7%-Profit Attributable to Owners of ParentProfit Margin91.94.4%107.14.7%+15.1+0.3 pts+16.5%-EBITDAEBITDA Margin168.98.2%266.211.6%+97.3+3.4 pts+57.7%-FCF-181.2-85.7+95.5-(billion yen, except where otherwise stated)1H FY2024 Financial Results by SegmentOrder IntakeRevenueBusiness Profit1HFY2024YoY1HFY2024YoY1HFY2024YoYEnergy Systems (Energy)1,306.7+225.6832.1+71.2103.2+61.5Plants & Infrastructure Systems (P&I)599.4+176.6379.1+12.128.1+12.0Logistics, Thermal & Drive Systems (LT&D)657.6+7.6632.8-0.526.9-9.7Aircraft, Defense & Space (ADS)802.1-197.2431.7+112.744.0+16.5Others, Corporate & Eliminations (OC&E)17.5+33.822.2+33.2-13.8+7.1Total3,383.5+246.42,298.1+228.8188.4+87.4In Energy, order intake increased by ¥225.6 billion YoY as Gas Turbine Combined Cycle (GTCC) and Aero Engines continued to see strong demand. Contracts for nine large frame gas turbine units were concluded in the first half, with the largest YoY growth seen in the Americas. Revenue increased by ¥71.2 billion YoY mainly from large volume in Aero Engines and steady project execution in GTCC and Nuclear Power. Margin improvements in GTCC and Steam Power, together with higher revenue and a rebound from 1H FY2023 one-time expenses in Aero Engines, as well as stable performance in Nuclear Power served to increase segment business profit by ¥61.5 billion YoY.In P&I, order intake was up ¥176.6 billion YoY due to strength in Metals Machinery, Machinery Systems, and Waste-to-Energy Systems. Revenue grew by ¥12.1 billion as Metals Machinery continued to work through its extensive backlog. Margin improvements in Engineering and Machinery Systems, combined with increased revenue in Metals Machinery helped to raise segment business profit by ¥12.0 billion YoY.In LT&D, revenue was down ¥0.5 billion YoY due to fewer unit deliveries in Logistics Systems. This issue, combined with additional costs caused by supply chain disruption in Turbochargers resulted in a ¥9.7 billion decline in segment business profit.In ADS, order intake decreased by ¥197.2 billion YoY in response to extremely large orders volume in 1H FY2023 in Defense & Space. Revenue was up ¥112.7 billion YoY mainly due to growth in Aircraft & Missile Systems in Defense & Space. Higher unit deliveries and positive impact from the depreciation of the yen in Commercial Aircraft also served to increase revenue. The factors affecting revenue also served to raise segment business profit by ¥16.5 billion YoY.　FY2024 Earnings ForecastMHI revised its guidance for the period ending March 31, 2025, increasing the target for order intake by ¥200 billion over the previous announcement made August 6, 2024. This was in response to steady progress mainly in Energy. Totals for all other financial indicators remained unchanged, while business profit targets for Energy, P&I, and LT&D were updated.(billion yen, except where otherwise stated)FY2024 Earnings ForecastFY2023ActualFY2024Forecast(Previous)FY2024Forecast(Revised)Revised vs.PreviousOrder Intake6,684.05,800.06,000.0+200.0Revenue4,657.14,900.04,900.0-Profit from Business ActivitiesProfit Margin282.56.1%350.07.1%350.07.1%--Profit Attributable to Owners of ParentProfit Margin222.04.8%230.04.7%230.04.7%--ROE11.1%10%10%-EBITDAEBITDA Margin432.69.3%500.010.2%500.010.2%--FCF200.1-100.0-100.0-Dividends20 yen(Note)22 yen22 yen-FY2023 Actual dividends (¥200/share) shown here adjusted retroactively to 1/10 of original value to reflect the 10-for-1 stock split effective April 1, 2024.　(billion yen, except where otherwise stated)FY2024 EarningsForecast by SegmentOrder IntakeRevenueBusiness ProfitPreviousRevisedPreviousRevisedPreviousRevisedEnergy1,850.02,000.01,750.01,750.0170.0180.0P&I900.0900.0800.0800.030.040.0LT&D1,350.01,350.01,350.01,350.080.060.0ADS1,700.01,700.0950.0950.080.080.0OC&E0.050.050.050.0-10.0-10.0Total5,800.06,000.04,900.04,900.0350.0350.0CFO Message"In the first half of this fiscal year, MHI continued the strong growth trend started in the first quarter, with order intake, revenue, business profit, and net income all up year-on-year," Hisato Kozawa, MHI Chief Financial Officer commented. Kozawa continued, "In terms of order intake, GTCC and Aero Engines in Energy, and Metals Machinery in P&I were stand-outs, enabling YoY orders growth despite the extremely high level achieved during the same period last year in Defense & Space. Revenue was up mainly in Energy and ADS as these segments steadily executed on their large order backlogs. These revenue increases, combined with margin improvements and depreciation of the yen helped us to greatly increase progress toward our business profit guidance of ¥350 billion.""Based on our results through September of this year, especially in Energy, we have increased our full-year order intake guidance by ¥200 billion," Kozawa went on. "We have also updated the business profit forecast for three of our segments in order to reflect the faster progress seen in Energy and P&I, and the slightly lagging performance in LT&D. All other targets have been restated. Looking forward to the remaining two quarters, we aim to outperform current business profit guidance by continuing the strong trends from the first half while effectively controlling one-time expenses."Attachment 1: 1H FY2024 Financial ResultsFinancial Results (444 KB)Attachment 2: Presentation Materials of Financial ResultsPresentation Materials (888 KB)Downloadable PDF of this press releasePress Release (168 KB)　Note regarding forward looking statements:Forecasts regarding future performance outlined in these materials are based on judgments made in accordance with information available at the time they were prepared. As such, these projections include risk and uncertainty. Investors are recommended not to depend solely on these projections when making investment decisions. Actual results may vary significantly from these projections due to a number of factors, including, but not limited to, economic trends affecting the Company's operating environment, fluctuations in the value of the Japanese yen to the U.S. dollar and other foreign currencies, and trends in Japan's stock markets. The results projected here should not be construed in any way as a guarantee by the Company.About MHI GroupMitsubishi Heavy Industries (MHI) Group is one of the world’s leading industrial groups, spanning energy, smart infrastructure, industrial machinery, aerospace and defense. MHI Group combines cutting-edge technology with deep experience to deliver innovative, integrated solutions that help to realize a carbon neutral world, improve the quality of life and ensure a safer world. For more information, please visit www.mhi.com or follow our insights and stories on spectra.mhi.com. Copyright 2024 JCN Newswire via SeaPRwire.com.