作者: sarah

JCB Becomes Sole Sponsor of New Large-Scale Japanese-Themed Establishment in Plaza Senayan, Jakarta’s Luxury Mall

TOKYO & JAKARTA, Dec 6, 2024 - (JCN Newswire via SeaPRwire.com) - JCB International Co., Ltd., the international operations subsidiary of JCB Co., Ltd., and PT. JCB International Indonesia, a subsidiary of JCB International Co., Ltd. (collectively referred to as "JCB"), have entered into an exclusive sponsorship agreement with PT Senayan Trikarya Sempana (STS) for Yashinoki Yokocho, a Japanese food court and Japanese travel information center set to open in Plaza Senayan, the luxury shopping mall in Indonesia.Prior to the soft opening on December 20, 2024, on December 6, 2024, JCB hosted the Japan Event in collaboration with Japanese restaurants that will open in Yashinoki Yokocho, local governments and Japanese commercial establishments that aim to attract inbound tourists, and multiple Japanese companies operating in Indonesia. The event invited famous Indonesian Key Opinion Leaders (KOLs) to discuss Japanese content and the appeal of traveling to Japan, deepening the understanding of the importance of Yashinoki Yokocho in providing a Japan experience while staying in Indonesia.JCB's Initiatives at Yashinoki YokochoYashinoki Yokocho, located in Plaza Senayan, will feature 14 stores, including Japanese restaurants opening their first location in Indonesia and a JCB SUGOI JAPAN booth, allowing visitors to experience an authentic Japanese atmosphere and enjoy real Japanese cuisine in Indonesia. The JCB SUGOI JAPAN booth will serve as an information center for travel to Japan and will also provide an opportunity for those interested to apply on the spot for JCB Cards with travel benefits in Japan.As the sole sponsor of Yashinoki Yokocho, JCB will develop various programs for JCB cardmembers in Yashinoki Yokocho, including:1. Sharing Information to promote travel to Japan2. Promotions with benefits and raffle for trip to Japan based on card usage3. Japan-related eventsJCB aims to further appeal to Indonesia's Japan enthusiasts by showcasing the unique charm of Japan.Background of SponsorshipIn recent years, Indonesia has experienced remarkable economic growth, with a particularly notable expansion of its affluent class. Many of these affluent customers have a strong interest in Japan, prompting JCB to focus on providing unique Japanese value under the slogan "SUGOI JAPAN". With the growth of the Japanese inbound market, JCB has been offering comprehensive services through partnerships with Japanese companies in both Indonesia and Japan.This sponsorship was accomplished through the aligned visions of STS to enhance services for visitors to Plaza Senayan and JCB to deliver its distinctive value to Indonesian customers. JCB will continue to expand its unique Japanese value and strive to become a leading payment brand.Concept of SUGOI JAPANJCB has been developing unique services with the slogan "SUGOI JAPAN", including 3 categories "VISIT JAPAN", "JCB DAY", and "JAPAN DINING".About Plaza Senayan and STSOperating since 1996, Plaza Senayan is a luxury mall in Jakarta featuring over 200 tenants, including luxury brands, restaurants, and cafes. It has consistently met the diverse needs of Indonesian customers. Plaza Senayan is operated by STS, established as a subsidiary of Kajima Corporation in 1990, as a core facility of the large-scale Senayan Square complex developed on approximately 190,000 square meters of state-owned land leased by Kajima Corporation, the parent company of STS. https://plaza-senayan.com/ About JCBJCB is a major global payment brand and a leading credit card issuer and acquirer in Japan. JCB launched its card business in Japan in 1961 and began expanding worldwide in 1981. Its acceptance network includes about 49 million merchants around the world. JCB Cards are now issued mainly in Asian countries and territories, with more than 158 million cardmembers. As part of its international growth strategy, JCB has formed alliances with hundreds of leading banks and financial institutions globally to increase its merchant coverage and cardmember base. As a comprehensive payment solution provider, JCB commits to providing responsive and high-quality service and products to all customers worldwide. For more information, please visit: www.global.jcb/en/ ContactAnna TakedaCorporate CommunicationsTel: +81-3-5778-8353Email: jcb-pr@info.jcb.co.jp Copyright 2024 JCN Newswire via SeaPRwire.com.

7 12 月, 2024

JCB Signs Memorandum of Understanding with Kobe Tourism Bureau for Inbound Tourism Promotion

TOKYO & JAKARTA, Dec 6, 2024 - (JCN Newswire via SeaPRwire.com) - JCB Co., Ltd., has signed a Memorandum of Understanding with the Kobe Tourism Bureau to promote inbound tourism. This partnership will strengthen the response to inbound demand mainly from affluent customers, primarily in the rapidly growing Indonesian market as a trial.Partnership OverviewBased on this memorandum, JCB and the Kobe Tourism Bureau will develop comprehensive tourism promotion strategies.Specifically, JCB and the Kobe Tourism Bureau will begin marketing trial initiatives aimed at stimulating consumption in Kobe with JCB Cards issued in Indonesia in January 2025. The partnership will offer special benefit programs at luxury hotels and traditional Japanese restaurants in Kobe, and it will gradually introduce exclusive benefits for JCB cardmembers at famous tourist spots in Kobe. Through these efforts, JCB and the Kobe Tourism Bureau aim to create added value for Japanese enthusiasts in Indonesia and improve their satisfaction during their stay in Kobe.In addition, the partnership will conduct behavioral analysis of inbound tourists using statistical data* on the consumption patterns of JCB cardmembers. Based on this information, JCB and the Kobe Tourism Bureau will effectively promote Kobe's attractions to Indonesian JCB cardmembers and work to build a model that strengthens the response to inbound demand through collaboration between the local government and the private sector.*Statistical data includes information on JCB Cards issued in Indonesia and other overseas markets, including card usage areas, industries and the amount of card transactions made in Kobe City.Background of the MemorandumIn recent years, Indonesia has seen remarkable economic development with a rapidly growing affluent class and increasing interest in high-quality tourism to Japan. JCB has been developing unique services with the slogan "SUGOI JAPAN", including 3 categories "VISIT JAPAN", "JCB DAY", and "JAPAN DINING".This partnership will further develop these initiatives by combining the Kobe Tourism Bureau's tourism promotion strategies with JCB's payment platform. JCB will work closely with the Kobe Tourism Bureau to enhance convenience and stimulate consumption by tourists from Indonesia. By maximizing the knowledge and networks of both parties, JCB and the Kobe Tourism Bureau will contribute to Kobe's tourism promotion and sustainable economic development. In addition, JCB aims to become a leading payment brand by developing unique Japanese value propositions with the slogan "SUGOI JAPAN".About JCBJCB is a major global payment brand and a leading credit card issuer and acquirer in Japan. JCB launched its card business in Japan in 1961 and began expanding worldwide in 1981. Its acceptance network includes about 49 million merchants around the world. JCB Cards are now issued mainly in Asian countries and territories, with more than 158 million cardmembers. As part of its international growth strategy, JCB has formed alliances with hundreds of leading banks and financial institutions globally to increase its merchant coverage and cardmember base. As a comprehensive payment solution provider, JCB commits to providing responsive and high-quality service and products to all customers worldwide. For more information, please visit: www.global.jcb/en/ ContactAnna TakedaCorporate CommunicationsTel: +81-3-5778-8353Email: jcb-pr@info.jcb.co.jp Copyright 2024 JCN Newswire via SeaPRwire.com.

7 12 月, 2024

服务当先 ESG引领 顺丰控股构建可持续发展力

香港, 2024年12月5日 - (亚太商讯 via SeaPRwire.com) - 据明报报道,当前,全球物流行业正在经历多维度的转变,随着市场需求日趋复合多元化,客户更倾向于更复杂、一站式、高质量及国际化的物流服务。而在亚洲,整个物流行业及其大多数细分领域仍然高度分散,此种背景下,顺丰控股(6936.HK)这样的领先综合物流企业将受惠于不断涌现的战略整合机遇,获得更大发展空间。在国际化和开放性兼具的香港资本市场,顺丰控股的上市,不仅为港股物流板块注入了新鲜血液,也带来极具长期投资价值的稀缺龙头标的。一流服务提升产品溢价 长期领跑行业身为一家全球领先的综合物流服务提供商,顺丰控股提供全面的端到端物流解决方案。根据弗若斯特沙利文报告,按2023年收入计,公司在中国及亚洲多个物流细分领域均处于市场领先地位。成立31年来,凭借领先行业的速度、一贯可靠的服务和以客户为中心的理念,顺丰控股从竞争对手中脱颖而出,并使公司的产品能够保有溢价,从而获得可观的利润增长。一方面,公司为客户提供快捷的时效配送服务,时效快递是其旗舰产品,也是综合物流服务的基础。同时,直营业务模式可以确保对运营及资源分配的全面把控,让服务高度可靠。公司始终将客户利益放在首位,以客户为中心,努力与客户建立紧密联系,提供有温度的服务。因为一流的服务,顺丰品牌广受认可,已经成为一个日常用语,「顺丰给你」也由此成为「快递给你」的代名词。截至2024年6月30日,公司拥有约220万活跃月结客户及约6.99亿散单客户,根据弗若斯特沙利文报告,该两项数据在亚洲所有物流服务提供商中均为最高。2024年,顺丰控股获评《财富》最受赞赏的中国公司第二位。践行企业社会责任 ESG治理广获认可快递物流业是国民经济的大动脉,覆盖生产制造和生活消费各个领域,在助力制造业转型升级、满足人们对于美好生活的需要及提升人们生活消费水平方面发挥着重要作用。顺丰控股将企业发展和社会责任紧密联系,积极贡献可持续力量。在独特的企业文化熏陶下,顺丰控股的收派员被亲切地称为「一哥╱ 一姐」,他们在尽职履行本职工作的同时,时常在人们危难之际伸出援手,为构建和谐社会作出努力贡献,也因此取得了公众的信任。在地震、洪水等自然灾害和其他极端情况下,顺丰控股总是冲在第一线,帮助社会大众快速恢复正常的生产生活。此外,公司通过提供各种物流服务带动农民产业创收,为其拓宽产品销售渠道,赋能其数字化转型,助力乡村振兴,促进共同富裕。不仅如此,顺丰控股还在ESG方面做出诸多努力,从推广绿色运输、在物流产业园使用清洁能源、倡导绿色包装,到赋能员工、倡导多元共融及推动乡村振兴,获得了广泛认可。自2022年起,公司连续三年入选《财富》杂志的中国ESG影响力榜,是唯一上榜的快递物流企业。放眼长远,顺丰控股将顺应行业发展大势,进一步优化服务产品,不断加强护城河,并服务国家战略,深化ESG治理,推动长期、可持续及具有盈利性的增长。 Copyright 2024 亚太商讯 via SeaPRwire.com.

5 12 月, 2024

“LEQEMBI” (Lecanemab) Approved for the Treatment of Early Alzheimer’s Disease in Mexico

TOKYO and CAMBRIDGE, Mass., Dec 5, 2024 - (JCN Newswire via SeaPRwire.com) -  Eisai Co., Ltd. and Biogen Inc. announced today that the Federal Commission forthe Protection Against Sanitary Risk (COFEPRIS) in Mexico has approved humanized anti-soluble aggregated amyloid-beta (Aβ) monoclonal antibody “LEQEMBI®” (lecanemab) for the treatment of early Alzheimer’s disease (AD)*.LEQEMBI selectively binds to soluble Aβ aggregates (protofibrils**), as well as insoluble Aβ aggregates (fibrils) which are amajor component of Aβ plaques, thereby reducing both Aβ protofibrils and Aβ plaques in the brain. LEQEMBI is the first approved treatment shown to reduce the rate of disease progression and to slow cognitive and functional decline through this mechanism. LEQEMBI is also approved and being marketed in the U.S., Japan, China, South Korea, Hong Kong, Israel, the United Arab Emirates, and Great Britain.LEQEMBI’s approval is based on the large global Phase 3 Clarity AD study. In the Clarity AD study,LEQEMBI met its primary endpoint and all key secondary endpoints with statistically significant results.(1),(2)Approximately 1.3 million people in Mexico are estimated to suffer from AD, accounting for 60-70% of all dementia diagnoses.3 AD most commonly affects individuals over the age of 65.(3)Eisai serves as the lead of LEQEMBI development and regulatory submissions globally with both Eisai and Biogen co-commercializing and co-promoting the product and Eisai having final decision-making authority. Eisai and Biogen will co-commercialize and co-promote LEQEMBI in Mexico.*Collectively referred to mild cognitive impairment due to AD or mild AD dementia.**Protofibrils are believed to contribute to the brain injury that occurs with AD and are considered to be the most toxic form of Aβ, having a primary role in the cognitive decline associated with this progressive, debilitating condition.(4) Protofibrils cause injury toneurons in the brain, which in turn, can negatively impact cognitive function via multiple mechanisms, not only increasing the development of insoluble Aβ plaques but also increasing direct damage to brain cell membranes and the connections that transmit signals between nerve cells or nerve cells and other cells. It is believed the reduction of protofibrils may prevent the progression of AD by reducing damage to neurons in the brain and cognitive dysfunction.(5)About lecanemab (LEQEMBI®)Lecanemab is the result of a strategic research alliance between Eisai and BioArctic. It is a humanized immunoglobulingamma 1 (IgG1) monoclonal antibody directed against aggregated soluble (protofibril) and insoluble forms of amyloid-beta (Aβ).Lecanemab is approved and being marketed in the U.S., Japan, China, South Korea, Hong Kong, Israel, the United Arab Emirates and Great Britain for the treatment of Alzheimer’s disease (AD) in patients with Mild Cognitive Impairment (MCI) ormild dementia stage of disease (collectively referred to as early AD). The treatment’s approvals in these countries was based onPhase 3 data from Eisai’s global Clarity AD clinical trial, in which it met its primary endpoint and all key secondary endpoints with statistically significant results.1,2 The most common adverse events (>10%) in the lecanemab group were infusion reactions,ARIA-H (combined cerebral microhemorrhages, cerebral macrohemorrhages, and superficial siderosis), ARIA-E (edema/effusion), headache, and fall.Lecanemab is under regulatory review in 16 countries and regions, including the European Union. In November 2024, thetreatment received a positive opinion from the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) recommending approval.Since July 2020 the Phase 3 clinical study (AHEAD 3-45) for individuals with preclinical AD, meaning they are clinically normaland have intermediate or elevated levels of amyloid in their brains, is ongoing. AHEAD 3-45 is conducted as a public-private partnership between the Alzheimer's Clinical Trial Consortium that provides the infrastructure for academic clinical trials in AD and related dementias in the U.S, funded by the National Institute on Aging, part of the National Institutes of Health, Eisai and Biogen. Since January 2022, the Tau NexGen clinical study for Dominantly Inherited AD (DIAD), that is conducted by Dominantly Inherited Alzheimer Network Trials Unit (DIAN-TU), led by Washington University School of Medicine in St. Louis, is ongoing and includes lecanemab as the backbone anti- amyloid therapy.About the Collaboration between Eisai and Biogen for ADEisai and Biogen have been collaborating on the joint development and commercialization of AD treatments since 2014. Eisaiserves as the lead of lecanemab development and regulatory submissions globally with Eisai and Biogen co-commercializingand co-promoting the product and Eisai having final decision-making authority.About the Collaboration between Eisai and BioArctic for ADSince 2005, Eisai and BioArctic have had a long-term collaboration regarding the development and commercialization of AD treatments. Eisai obtained the global rights to study, develop, manufacture and market lecanemab for the treatment of AD pursuant to an agreement with BioArctic in December 2007. The development and commercialization agreement on the antibody lecanemab back-up was signed in May 2015.About Eisai Co., Ltd.Eisai's Corporate Concept is "to give first thought to patients and people in the daily living domain, and to increase the benefits that health care provides." Under this Concept (also known as human health care (hhc) Concept), we aim to effectively achieve social good in the form of relieving anxiety over health and reducing health disparities. With a global network of R&Dfacilities, manufacturing sites and marketing subsidiaries, we strive to create and deliver innovative products to target diseaseswith high unmet medical needs, with a particular focus in our strategic areas of Neurology and Oncology.In addition, we demonstrate our commitment to the elimination of neglected tropical diseases (NTDs), which is a target (3.3) of the United Nations Sustainable Development Goals (SDGs), by working on various activities together with global partners.For more information about Eisai, please visit www.eisai.com (for global headquarters: Eisai. Co., Ltd.), us.eisai.com (for U.S.headquarters: Eisai, Inc.) or www.eisai.eu (for Europe, Middle East, Africa, Russia, Australia and New Zealand headquarters:Eisai Europe Ltd.), and connect with us on X (global and U.S), LinkedIn (for global, U.S. and EMEA) and Facebook (global).About BiogenFounded in 1978, Biogen is a leading biotechnology company that pioneers innovative science to deliver new medicines to transform patients’ lives and to create value for shareholders and our communities. We apply deep understanding of human biology and leverage different modalities to advance first-in-class treatments or therapies that deliver superior outcomes. Our approach is to take bold risks, balanced with return on investment to deliver long-term growth.The company routinely posts information that may be important to investors on its website at www.biogen.com.Follow Biogen on social media – Facebook, LinkedIn, X, YouTube.Biogen Safe HarborThis news release contains forward-looking statements, about the potential clinical effects of lecanemab; the potential benefits, safety and efficacy of lecanemab; potential regulatory discussions, submissions and approvals and the timing thereof;the treatment of Alzheimer's disease; the anticipated benefits and potential of Biogen's collaboration arrangements with Eisai; the potential of Biogen's commercial business and pipeline programs, including lecanemab; and risks and uncertainties associated with drug development and commercialization. These statements may be identified by words such as "aim," "anticipate," "believe," "could," "estimate," "expect," "forecast," "intend," "may," "plan," "possible," "potential," "will," "would" and other words and terms of similar meaning. Drug development and commercialization involve a high degree of risk, andonly a small number of research and development programs result in commercialization of a product. Results in early-stage clinical studies may not be indicative of full results or results from later stage or larger scale clinical studies and do not ensure regulatory approval. You should not place undue reliance on these statements.These statements involve risks and uncertainties that could cause actual results to differ materially from those reflected in suchstatements, including without limitation unexpected concerns that may arise from additional data, analysis or results obtained during clinical studies; the occurrence of adverse safety events; risks of unexpected costs or delays; the risk of other unexpected hurdles; regulatory submissions may take longer or be more difficultto complete than expected; regulatory authorities may require additional information or further studies, or may fail or refuse toapprove or may delay approval of Biogen's drug candidates, including lecanemab; actual timing and content of submissions to and decisions made by the regulatory authorities regarding lecanemab; uncertainty of success in the development and potential commercialization of lecanemab; failure to protect and enforce Biogen's data, intellectual property and otherproprietary rights and uncertainties relating to intellectual property claims and challenges; product liability claims; and thirdparty collaboration risks, results of operations and financial condition. The foregoing sets forth many, but not all, of the factorsthat could cause actual results to differ from Biogen's expectations in any forward-looking statement. Investors should consider this cautionary statement as well as the risk factors identified in Biogen's most recent annual or quarterly report and in otherreports Biogen has filed with the U.S. Securities and Exchange Commission. These statements speak only as of the date of this news release. Biogen does not undertake any obligation to publicly update any forward-looking statements.References(1) Eisai presents full results of lecanemab Phase 3 confirmatory Clarity AD study for early Alzheimer's disease at Clinical Trials on Alzheimer's Disease (CTAD) conference. Available at: www.eisai.com/news/2022/news202285.html(2) van Dyck, H., et al. Lecanemab in Early Alzheimer’s Disease. New England Journal of Medicine. 2023;388:9-21. www.nejm.org/doi/full/10.1056/NEJMoa2212948(3) Secretaría de Salud. Enfermedad de Alzheimer, demencia más común que afecta a personas adultas mayores. Oct 2021. https://tinyurl.com/ttv486xx(4) Amin L, Harris DA. Aβ receptors specifically recognize molecular features displayed by fibril ends and neurotoxic oligomers. Nat Commun. 2021;12:3451. doi:10.1038/s41467-021-23507-z(5) Ono K, Tsuji M. Protofibrils of Amyloid-β are Important Targets of a Disease-Modifying Approach for Alzheimer's Disease. Int J Mol Sci. 2020;21(3):952. doi: 10.3390/ijms21030952. PMID: 32023927; PMCID: PMC7037706.MEDIA CONTACTSEisai Co., Ltd.Public Relations Department TEL : +81 (0)3-3817-5120INVESTOR CONTACTSEisai Co., Ltd.Investor Relations Department TEL: +81 (0) 3-3817-5122Biogen Inc.Jack Cox+ 1-781-464-3260public.affairs@biogen.comBiogen Inc.Stephen Amato+ 1-781-464-2442IR@biogen.com Copyright 2024 JCN Newswire via SeaPRwire.com.

5 12 月, 2024

DENSO Signs Memorandum of Understanding with Canatu of Finland for Practical Application of Carbon Nanotube Technology

KARIYA, JAPAN, Dec 4, 2024 - (JCN Newswire via SeaPRwire.com) - DENSO Corporation has recently signed a Memorandum of Understanding (MOU) with Canatu to advance the practical application of carbon nanotube technology. By strengthening their partnership, the two companies aim to deepen their collaboration to contribute to the advancement of autonomous driving technology and the realization of carbon neutrality.As autonomous driving technology continues to evolve, vehicles must accurately detect their surroundings using cameras and other sensors. However, issues such as frost and condensation can obstruct visibility and complicate detection. To address these challenges, DENSO is developing products that utilize transparent conductive films made from flexible, transparent materials. Carbon nanotube technology is key to these developments.Carbon nanotubes are carbon-based materials with extremely fine structures, characterized by high strength, light weight, and excellent electrical and thermal conductivity. They hold great promise for a wide range of applications. Canatu has innovative technology that enables the efficient production of high-purity carbon nanotubes using proprietary materials and has strengths in transparent conductive film formation.DENSO has been collaborating with Canatu by combining Canatu’s advanced transparent conductive film technology with DENSO’s expertise in automotive technology and mass production. In April this year, the companies successfully developed a reactor* at Canatu’s production facility in Finland, significantly enhancing the productivity of carbon nanotubes. They have also been jointly developing transparent heaters for vehicle cameras and windshields. Moving forward, DENSO and Canatu will continue to drive efforts toward the commercialization of transparent heaters while also expand their application to environmental technologies. Their goal is to establish technologies that contribute to carbon neutrality.Key Areas of CollaborationDENSO and Canatu will accelerate initiatives in the following three areas to achieve practical applications of carbon nanotube technology:1. Research and DevelopmentDevelop new applications, including transparent heaters and solar power technologies, utilizing carbon nanotubes.2. Mass Production TechnologiesCollaborate on improving manufacturing equipment and processes to achieve the quality required for mass production.3. Global Supply Chain DevelopmentBegin exploring the establishment of a reliable supply system to ensure the stable and consistent delivery of high-quality products.DENSO will continue advancing technology development in collaboration with partners across various fields, contributing to sustainable mobility for people and the planet.*Reactor: Equipment used for manufacturing carbon nanotubes. Copyright 2024 JCN Newswire via SeaPRwire.com.

5 12 月, 2024

中信国际电讯CPC荣获三项业界大奖 内外展现网络安全实力

香港, 2024年12月4日 - (亚太商讯 via SeaPRwire.com) - 中信国际电讯集团有限公司(「中信国际电讯」,香港交易所股份代号:1883)全资拥有的中信国际电讯(信息技术) 有限公司(「中信国际电讯CPC」) 宣布勇夺三项业界大奖 ,肯定中信国际电讯CPC深耕网络安全的优质表现,表扬专业团队深厚的行业知识与技术、员工高度的网络安全意识及前瞻的创新解决方案,以满足市场对不断增长的网络安全需求 ,应对日益猖獗的网络威胁和挑战。三项业界大奖包括:- 香港互联网注册管理有限公司(HKIRC)「共建员工防火墙」嘉许计划2024 白金级奖 ;- Fortinet「2024年度最佳托管安全服务供应商」奖项 (Top MSSP of the Year 2024);- Green Radar 「2024 年度最佳企业业务合作伙伴」奖项 (Top Partner Enterprise Business FY24 )中信国际电讯 CPC 行政总裁黄政华先生表示:「该三项业界大奖展示我们对推动内部'员工防火墙'文化的承诺,同时通过我们的网络安全专家团队向企业客户提供全面的解决方案,彰显了我们在内外实力上的坚实基础。业界对我们的肯定将激励我们持续提升网络安全创新方案,期望带来更多的市场机遇,共同推动行业的高质量发展。我们有信心,旗舰信息安全解决方案'TrustCSI™ 3.0云网神盾'在网络安全市场保持优势竞争力,巩固我们作为前沿网络安全领导者地位。」  HKIRC「共建员工防火墙」嘉许计划香港互联网注册管理有限公司 (HKIRC) 与国际信息系统审计协会中国香港分会 (ISACA) 联合举办的「共建员工防火墙」嘉许计划圆满举行 ,参加机构涵盖了银行、物业管理、零售等行业的中小企及大型企业。该计划旨在表彰得奖企业在过去一年内意识到网络安全重要性并积极提升员工网络安全意识的努力。「共建员工防火墙」嘉许计划鼓励更多机构采取积极的措施推广「员工防火墙(Human Firewall)」理念 ,通过多种渠道如培训、政策、沟通、演习等提高员工防护意识。最高级别白金级奖需要符合所有5项评审标准,包括网络安全培训 、网络钓鱼演习 、网络安全政策 、通报渠道及网络安全资讯传递 。中信国际电讯CPC 荣获最高级别之白金级认证,表扬其致力过去不但在网络安全技术上不断提升、在系统和政策方面全面优化,并推出'TrustCSI™ 3.0 云网神盾'信息安全服务,创新的服务框架,配备主动防御技术以应对快速迭代的网络威胁。 同时培养员工对网络安全意识文化的决心,通过全球员工强度训练及网络安全演练,构建为公司的第二道防线,防范并能有效应对不断变化的网络威胁。 共创共赢, 构建更坚固的防御生态圈此外,中信国际电讯CPC 荣获两家网络安全服务生态圈伙伴Fortinet及Green Radar颁发多个卓越奖项,彰显其在全球性合作策略和网络安全领域高质量的协作能力,通过持续的技术创新和与生态圈合作伙伴的紧密合作,中信国际电讯CPC得以不断提升产品和服务质量,以满足市场对网络安全方案的需求并超越竞争对手。其中包括在 2023 年推出的 TrustCSI™ 3.0 云网神盾,通过智能技术重塑安全运营中心(SOC)的核心服务能力,为企业提供主动式防御,将AI 应用融入其业务中,优化智能运营。首先, Fortinet颁发的「2024 年度最佳托管安全服务供应商」奖项肯定了中信国际电讯CPC 前沿的托管安全服务,超越业界标准。另外,Green Radar「2024 年度最佳企业业务合作伙伴」奖项表扬中信国际电讯CPC与合作伙伴携手推动创新解决方案,以满足企业客户独特的网络安全需求。积极提升内外网络安全及创新技术中信国际电讯CPC无论对内或对外,一直积极展现高水平的网络安全能力。在对内方面,中信国际电讯CPC致力培育员工网络安全意识,而员工在工作上时刻保持警惕和采用主动的防御措施,体现了对网络安全的最佳实践,以保护公司的数资产。在对外方面,中信国际电讯CPC致力成为企业可信赖的TechOps 信息安全赋能者,旗下的网络安全专家团队具备前瞻思维和追求卓越成就的精神,通过专业服务和创新定制的解决方案,助力客户轻松及灵活地应对瞬息万变的数字环境。秉持'创新不断'服务理念,中信国际电讯CPC持续将人工智能技术整合到信息安全产品组合中,提供前沿网络安全解决方案以应对愈发猖獗的网络威胁。中信国际电讯CPC最新的TrustCSI AI渗透测试(AI Pentest)服务如同网络AI扫地机器人,7x24全自动化工作,协助企业找出网络中的致命漏洞,建立强大的防御机制 。为了强化企业客户内外部的漏洞,中信国际电讯CPC特别提供了一个最新内外评估组合方案,协助客户通过对内的AI渗透测试服务,同时,进行攻击面管理 (Attack Surface Management),增强公司对外部漏洞的抵御能力,并系统地优化漏洞识别、排列漏洞优次、补救和持续监控等攻击,通过多管齐下的防护措施降低潜在的网络攻击风险,提升企业安全管理策略。详情可浏览https://www1.citictel-cpc.com/promotion/2411XmasOffer/index-SC.html中信国际电讯CPC简介中信国际电讯(信息技术)有限公司(「中信国际电讯CPC」)是中信国际电讯集团有限公司(香港交易所股份代号:1883)的全资附属公司,公司一直矢志透过先进技术及旗舰解决方案,包括TrueCONNECT专用网络服务、TrustCSI信息安全解决方案、DataHOUSE全球统一云数据中心解决方案及SmartCLOUD云端运算解决方案,为全球跨国企业提供综合数码解决方案, 满足不同行业的ICT服务需求。凭借「创新-不断」的服务理念,中信国际电讯CPC积极利用创新技术,提炼'技术赋能',将人工智能、扩增实境、大数据、物联网和其他尖端新兴技术,融合深度学习及智能数据分析技术,转化为'数据赋能'生成式AI+应用,重塑企业智能营运之旅。中信国际电讯CPC以「服务在地,连接全球」优势,承诺为客户提供优质的一站式ICT服务。全球化网络资源连接近170个服务据点、60多个SDWAN 网关;21个云服务中心、30多个数据中心及3个全天候运作的安全运作中心,服务遍布约160个国家和地区,无缝连接亚洲、欧美、非洲、中东以及中亚等地区。透过全球化服务布局,多年不断深耕各个行业与领域经验,一系列国际标准服务认证(SD-WAN Ready, ISO 9001、14001、20000、27001 及27017),确保为企业提供国际化标准及服务资源,专业的在地服务及交付能力,同时,优质的客户体验和服务质量,成为领先的综合信息智能化服务供应商。请浏览www.citictel-cpc.com 获取更多资讯。传媒查询:Catherine Yuen中信国际电讯CPC(852) 2170 7536电邮:catherine.yuen@citictel-cpc.com Copyright 2024 亚太商讯 via SeaPRwire.com.

4 12 月, 2024

云顶新耀宣布治疗原发性膜性肾病的新型BTK抑制剂EVER001在1b/2a期临床试验阶段性数据中取得积极结果

- 在已完成36周治疗的低剂量组患者中,81.8%(9/11)的患者实现临床缓解,高剂量组中已完成24周治疗的患者已有85.7%(6/7)实现临床缓解。- 除低剂量组的1例患者外,其他所有完成36周治疗的低剂量组患者,以及所有经24周治疗的高剂量组患者分别在36周和24周都实现了免疫学完全缓解。- EVER001总体安全性和耐受性良好。未见在其他共价非可逆BTK抑制剂上观察到的有临床意义的不良事件,如出血、心律失常、严重感染、白细胞减少、血小板减少、严重肝功能损伤等。上海, 2024年12月4日 - (亚太商讯 via SeaPRwire.com) - 云顶新耀(HKEX 1952.HK)是一家专注于创新药研发、临床开发、制造和商业化的生物制药公司,今日宣布新一代共价可逆布鲁顿酪氨酸激酶(BTK)抑制剂 EVER001胶囊(又名:XNW1011)在治疗原发性膜性肾病(primary membranous nephropathy,pMN)的1b/2a期临床试验阶段性数据取得积极结果。直至9月13日的数据截止日期,结果显示,在已完成36周治疗的低剂量组患者中,81.8%(9/11)的患者实现临床缓解,高剂量组中已完成24周治疗的患者已有85.7%(6/7)实现临床缓解。除低剂量组的1例患者外,其他所有完成36周治疗的低剂量组患者,以及所有经24周治疗的高剂量组患者分别在36周和24周都实现了免疫学完全缓解。EVER001是一款适用于自身免疫性肾脏疾病的共价可逆BTK抑制剂。与共价不可逆BTK抑制剂相比,EVER001作为一款潜在的同类最佳产品,在保持高活性的同时具有高选择性,避免持续抑制带来的毒副作用。云顶新耀拥有这款产品用于肾病治疗的全球权益。EVER001治疗原发性膜性肾病的1b/2a期临床试验为一项正在进行中的中国研究。共有31名经肾脏活检证实的抗-PLA2R自身抗体阳性的原发性膜性肾病患者分别入组低剂量组和高剂量组,接受EVER001 共36周的治疗。截至2024年9月13日的数据分析,低剂量组的24小时蛋白尿几何平均值(最小二乘法)在36周相较于基线下降78.3%,而高剂量组在24周即出现73.8%的下降。抗-PLA2R自身抗体水平在数据截止日期时已达到接近100%的下降,而早在低剂量组的24周和高剂量组的12周,抗-PLA2R自身抗体下降已超过90%。EVER001总体安全性和耐受性良好。未见在其他共价非可逆BTK抑制剂上观察到的有临床意义的不良事件,如出血、心律失常、严重感染、白细胞减少、血小板减少、严重肝功能损伤等。云顶新耀首席执行官罗永庆表示:"非常高兴看到EVER001在此次公布的阶段性数据中取得了积极的结果。这显示了EVER001作为新一代BTK抑制剂,对包括原发性膜性肾病在内的多种自身免疫性肾病治疗的巨大潜力。迄今为止,全球没有获批原发性膜性肾病适应症的药物。作为首个公布的具有全球权益的管线产品数据,EVER001在原发性膜性肾病患者中取得的阶段性结果令人鼓舞。我们也期待该1b/2a期临床试验的完成及更多相关数据的发表。我们将继续推进EVER001的全球临床开发,以最快速度满足患者的临床需求。"膜性肾病为成人肾病综合征常见的病理类型,在我国的患病率呈逐年升高的趋势,是发病率仅次于IgA肾病的原发性肾小球肾炎1。我国目前有约200万原发性膜性肾病患者,而在美国约有8万-10万患者,欧洲约8万患者,日本约4万患者。目前全球没有获批此适应症的药物。超过1/3的原发性膜性肾病患者最终将进展为终末期肾病,全球亟需研发能提高治疗缓解率、降低高复发率、减少慢性肾毒性风险的治疗药物。此项1b/2a期临床试验于2022年9月获得中国国家药品监督管理局药品审评中心批准,用于评价EVER001在蛋白尿为特征的肾小球疾病的中国患者中的安全性、疗效、药代动力学和药效学。此前公布的中国抗体制药在中国健康受试者中进行的1期研究结果表明,EVER001具有高选择性、优异的药代动力学特征、良好的安全性特征以及强大的靶点结合力。关于EVER001EVER001胶囊(又名:XNW1011)是新一代共价可逆的布鲁顿酪氨酸激酶 (BTK)抑制剂,正在全球范围内开发用于治疗肾病。BTK是B 细胞受体信号通路的重要组成部分,可调节 B 淋巴细胞的存活、激活、增殖和分化。应用小分子抑制剂靶向 BTK 是治疗 B 细胞淋巴瘤和自身免疫性疾病的有效选择。中国抗体制药在国内完成的健康受试者I期研究结果表明,EVER001具有高选择性、优异的药代动力学特征、强大靶点结合力和良好的安全性特征,研究结果支持其进一步临床开发。根据与信诺维医药和中国抗体制药的独家许可协议,云顶新耀拥有在全球开发、生产和商业化EVER001用于治疗肾病的权利。投资人会议公司将举行中英文投资人线上会议,公布新一代共价可逆布鲁顿酪氨酸激酶(BTK)抑制剂 EVER001胶囊治疗原发性膜性肾病的1b/2a期临床试验数据。云顶新耀拥有EVER001在全球范围内开发用于治疗肾病领域的权益。英文场次将于北京时间2024年12月4日上午9时(美国东部时间12月3日晚上8时)举行;中文场次将于北京时间同日上午10:30时(美国东部时间12月3日晚上9:30时)举行。英文会议:会议时间:北京时间2024年12月4日,星期三,上午9时(美国东部时间12月3日晚上8时)提前注册链接:https://www.acecamptech.com/eventDetail/60510700会议直播链接:https://www.acecamptech.com/meeting_live/70512679/774680?event_id=60510700同时,参会者也可以使用以下拨入信息拨入电话会议:美国:+1-646-2543594 (EN)中国大陆:+86-10-58084166 (EN),+86-10-58084199 (CN)中国香港:+852-30051313 (EN),+852-30051355 (CN)英国:+44-12-1368-0466 (EN)国际:+1-866-6363243 (EN)会议代码:842080中文会议:会议时间:北京时间2024年12月4日,星期三,上午10:30时(美国东部时间12月3日晚上9:30时)会议直播链接: https://s.comein.cn/n3arj55s同时,参会者也可以使用以下拨入信息拨入电话会议:美国:+1-646-3578788,+1-408-7093255中国大陆:400-969-8928,400-806-3263中国香港:+852-301-83602中国台湾:+886-226563394,+886-277417882新加坡:+65-64075649,+65-66220840英国:+44-2070970018海外:+86-2362737123会议密码:377570英文会议结束后,您可以通过访问云顶新耀官网(http://www.everestmedicines.com)收听英文会议回放。关于云顶新耀云顶新耀是一家专注于创新药和疫苗研发、临床开发、制造和商业化的生物制药公司,致力于满足亚洲市场尚未满足的医疗需求。云顶新耀的管理团队在中国及全球领先制药企业从事过高质量研发、临床开发、药政事务、化学制造与控制(CMC)、业务发展和商业化运营,拥有深厚的专长和丰富的经验。云顶新耀已打造多款疾病首创或者同类最佳的药物组合,公司的治疗领域包括肾科疾病、感染性和传染性疾病、自身免疫性疾病。有关更多信息,请访问公司网站:www.everestmedicines.com。前瞻性声明本新闻稿所发布的信息中可能会包含某些前瞻性表述,乃基于本公司或管理层在做出表述时对公司业务运营情况及财务状况的现有看法、相信、和现有预期,可能会使用"将"、"预期"、"预测"、"期望"、"打算"、"计划"、"相信"、"预估"、"确信"及其他类似词语进行表述。这些前瞻性表述并非对未来业绩的保证,会受到风险、不确定性及其他因素的影响,有些乃超出本公司的控制范围,难以预计。因此,受我们的业务、竞争环境、政治、经济、法律和社会情况的未来变化及发展等各种因素及假设的影响,实际结果可能会与前瞻性表述所含资料有较大差别。本公司及各附属公司、各位董事、管理人员、顾问及代理未曾且概不承担更新该稿件所载前瞻性表述以反映在本新闻稿发布日后最新信息、未来项目或情形的任何义务,除非法律要求。参考文献:1.利妥昔单抗在膜性肾病中应用的专家共识,中华内科杂志2022年3月第61卷第3期。 Copyright 2024 亚太商讯 via SeaPRwire.com.

4 12 月, 2024

Honda and MIE Honda HEAT Hold Rally Event Ahead of the NTT Japan Rugby League One 2024-2025 Season

TOKYO, Dec 3, 2024 - (JCN Newswire via SeaPRwire.com) - Honda Motor Co., Ltd. and its rugby team, MIE Honda HEAT, today held a rally event at the Aoyama Welcome Plaza in the Honda Global Head Office in Tokyo, ahead of the NTT Japan Rugby League One 2024-2025 season, which begins on Saturday, December 21, 2024.At the event, Manabu Ozawa, a Managing Executive Officer of Honda concurrently serving as Executive Advisor of MIE Honda HEAT, introduced the Honda vision for its sports activities – to increase the number of people who take on challenges through sports activities and make the lives of all people more enjoyable. He also announced the MIE Honda HEAT team value – “BIND” All Dreams – which was newly established in the pursuit of the team’s vision to become “the strongest, most respected, most loved” team. The “team value” represents the team’s desire to “take on challenges and chase dreams together with all people involved with MIE Honda HEAT.”Other key staff members and players on the team who expressed their strong passion and commitment for the upcoming season included Head Coach Kieran Crowley, General Manager Yoshihito Maeda, the new captain Takumi Fujii, and other key players, including Lemeki Lomano Lava, who returned to the team for the first time in four years. The MIE Honda HEAT was founded in 1961, as the Honda rugby team based in the City of Suzuka, in Mie Prefecture, Japan. Since last season (2023-2024 season), the team has been taking on challenges competing in Division 1, the top division of the Japan Rugby League One. Working toward its goal to become the No. 1 team in Japan in three years’ time, the MIE Honda HEAT has been pursuing continuous initiatives to enhance its strength. In the meantime, in September of this year, the team announced its plan to relocate the base of activities to Utsunomiya City, Tochigi Prefecture sometime prior to the start of the 2026-2027 season, in order to offer more people the opportunity to see the team and get involved in its challenges toward its goal.Based on the company’s vision for its sports activities, Honda will continue to support various athletes who take on challenges toward the realization of their own dreams.Comment of Manabu Ozawa, Managing Executive Officer of Honda Motor Co., Ltd.“Honda sports teams, including the Honda Running Team, have inspired many people this year with their remarkable achievements, expanding their activities from Japan to the world. Our rugby team, getting ready for its second season with the new head coach Kieran Crowley, has built a team structure that reflects the strong will of Coach Crowley to achieve our goal to become the No. 1 team in Japan in three years’ time. We are committed to strengthening MIE Honda HEAT as a sports team that represents Honda corporate culture, demonstrating the collective strengths and teamwork of Honda. In two years, the team is relocating the base of its activities to Tochigi Prefecture, and will continue to strive for further growth. MIE Honda HEAT will continue to take on bold challenges and prove the power of believing in “The Power of Dreams” by playing matches that move people’s hearts. Thank you in advance for your continued support and cheers in the 2024-25 season.”Comment of Kieran Crowley, Head Coach of MIE Honda HEAT“The 2023-24 season, my first year as head coach, was a very difficult one, with only one win out of 16 games. Based on what I perceived as our challenges throughout the season, I brought in 14 new players during the off-season and also added new coaches. As a result of intense competition for positions within the team and the rigorous training experienced by all players, we have built a team with strong physical capability and the stamina to play 80 minutes at full strength. With a goal to be ranked sixth or above in the league, we will further improve our performance in the 2024-25 season, which will start soon. Please keep your expectations high for the great effort and performance of MIE Honda HEAT!”MIE Honda HEAT official website: https://www.honda-heat.jp/ (Japanese/English)Honda Sports Activity website:https://global.honda/jp/brand/sports/ (Japanese)JAPAN RUGBY LEAGUE ONE:https://league-one.jp/ (Japanese)https://league-one.jp/en/ (English) Copyright 2024 JCN Newswire via SeaPRwire.com.

4 12 月, 2024

MHI Thermal Systems Receives “Minister of the Environment Award for Climate Action 2024”

TOKYO, Dec 3, 2024 - (JCN Newswire via SeaPRwire.com) - Mitsubishi Heavy Industries Thermal Systems, Ltd. (MHI Thermal Systems), a part of Mitsubishi Heavy Industries (MHI) Group, has received a Minister of the Environment Award for Climate Action 2024 for development of its JHT-Y/JHT-YI series of large-capacity centrifugal chillers adopting the HFO-1234yf refrigerant with a low GWP(1). The award, sponsored by the Japanese Ministry of the Environment, was presented in the Technological Development and Commercialization category. An awards ceremony took place in Tokyo on December 2.The Awards CeremonyThe Minister of the Environment for Climate Action Award program was renewed in 2020 to reflect recent trends in climate change measures and succeeded the Environment Minister's Awards for Global Warming Prevention Activity, which had been held since 1998. The awards are given annually to individuals or groups having made noteworthy contributions to climate change mitigation (measures to curb greenhouse gas emissions) and accommodation to climate change (measures to avert or reduce impacts from climate change). This 2024 award is MHI Thermal Systems' third to date: in 2019, the Company received an Environment Minister's Award for its high-efficiency centrifugal chiller ETI-Z series that adopt a low-GWP refrigerant(2); and in 2021, the Company garnered the award for development and promotion of an air-to-water type heat pump using a low-GWP refrigerant(3).The constant-speed JHT-Y and inverter-equipped JHT-YI are new series for large-capacity centrifugal chillers launched in June 2022. Both models in the series adopt the HFO-1234yf refrigerant with extremely low environmental impact (GWP below 1) and the capacities ranging from 300 to 5,400 refrigeration tons (RT)(4). The JHT-Y and JHT-YI are the first centrifugal chillers with capacities up to 5,400 RT commercially offered in Japan with a low-GWP refrigerant. With a newly designed compressor, outstanding efficiency has been achieved: the constant-speed model to achieve a maximum rated COP(5) of 6.4, the inverter-equipped model achieves an IPLV(6) of 8.8 and a maximum part load COP of 24.9. A smaller compressor size, together with the optimized centrifugal chiller structure layout, also contributes to the effective use of the space, enabling smooth installation from existing equipment. The replacement of an existing equipment using a higher-GWP HFC (hydrofluorocarbon) refrigerant with the JHT-YI can reduce annual energy consumption and CO2emissions by approximately 65%(7), contributing significantly to mitigating environmental impacts. The JHT-Y and JHT-YI models are also adaptable to a wide range of applications: air-conditioning, heating, as well as low-temperature and heating processes in beverage plants, etc.The HFO-1234yf refrigerant, which is also used in car air-conditioners and vending machines, has a GWP of below 1 and ODP(8) of zero, and is categorized as non-Freon refrigerant according to Japan's Revised Fluorocarbons Recovery and Destruction Law(9). For these reasons, it is not subject to this Law that regulates the Fluorocarbons' emissions into the atmosphere, recovery, and destruction after usage. Concerning an equipment with higher-GWP HFC refrigerant including HFC-134a, which was widely used before the revised legislation took effect, it has been made compulsory to reduce in both their production and usage volumes as it has a significant impact on global warming. In 2025 and onward, it is scheduled that the regulations on the supply of equipment with higher-GWP refrigerants to the market will be tightened further in the Japanese market, therefore, currently the demands for the equipment with low-GWP refrigerants, ex. the JHT-Y/JHT-YI series, are increasing and earlier upgrading is required in the market.MHI Thermal Systems is Japan's leading manufacturer of centrifugal chillers, having delivered numerous units for district cooling/heating, factory air-conditioning, etc. Going forward, the Company will continue to focus on developing high-performance products using low-GWP refrigerants covering - together with the small and medium-capacity ETI-Z series - a capacity span of 150 to 5,400 RT, as its way of contributing to environmental protection on a global scale.(1) GWP: global warming potential. CO2 is assigned a GWP of 1. The lower the GWP factor, the less impact on the environment.(2) For further information, refer to the following press release: https://www.mhi.com/news/191203.html(3) For further information, refer to the following press release: https://www.mhi.com/news/21112502.html(4) Capacity above 2,700 RT requires two compressors (parallel type).(5) COP: coefficient of performance as calculated based on Japanese Industrial Standards (JIS). The higher the COP, the higher the level of energy savings.(6) IPLV: integrated part load value, an indicator of the efficiency of an air-conditioner during part load operation. The higher the IPLV, the higher the level of energy savings.(7) Compared with our previous model (20 years ago)(8) ODP: ozone depletion potential, a coefficient expressing the relative amount of degradation to the ozone layer compared to trichlorofluoromethane (CFC-11), a refrigerant previously in wide use which has a fixed ODP of 1.0. The lower the ODP, the lower the destructive impact on the ozone layer.(9) This revised law, which took effect on April 1, 2015, stipulates rules for the rational use and proper management of fluorocarbons.JHT-Y/JHT-YI SeriesAbout MHI GroupMitsubishi Heavy Industries (MHI) Group is one of the world’s leading industrial groups, spanning energy, smart infrastructure, industrial machinery, aerospace and defense. MHI Group combines cutting-edge technology with deep experience to deliver innovative, integrated solutions that help to realize a carbon neutral world, improve the quality of life and ensure a safer world. For more information, please visit www.mhi.com or follow our insights and stories on spectra.mhi.com. Copyright 2024 JCN Newswire via SeaPRwire.com.

4 12 月, 2024

从亚洲到全球 顺丰控股开启新一轮价值跃升

香港, 2024年12月3日 - (亚太商讯 via SeaPRwire.com) - 在中国物流行业,顺丰控股(6936.HK)是当之无愧的领跑者。公司从时效快递起家,通过直营模式,确立在中高端时效快递领域的领先地位,并率先进行了资源全球化布局,进行业务的多元化布局,逐步发展成为业务覆盖物流行业各核心细分领域的综合物流服务龙头。2023年,顺丰控股实现营收人民币2,584亿元,在全球综合物流服务提供商中仅次于联合包裹服务公司(UPS)、敦豪(DHL)和联邦快递(FedEx)。站在行业变革的关键时刻,顺丰控股将目光从中国及亚洲扩展至全球市场。11月27日,公司于联交所上市,以期藉助这一契机,加速全球化战略的推进,助力公司在高质量发展的基础上,实现新一轮的跃升。新老业务协同发展 新业务陆续迎来盈利增长顺丰控股全方位布局物流业务,其业务版图覆盖时效快递、经济快递、快运、冷运物流、同城即时配送以及供应链和国际服务领域,在各业务领域均建立领先竞争力。其中,时效快递作为顺丰控股基本盘,2023年市场份额高达63.9%。过往期间,公司持续夯实时效服务竞争力,同时不断拓展新兴产业客群和新业务场景,营收稳步增长,2024年上半年该项业务营收同比增加5.6%。同时,顺丰控股新业务也陆续收获了耕耘果实。快运业务方面,顺丰控股在客户便利性、时效性、准时性等方面持续打造竞争优势,大件业务于2022年首次实现转盈,2023年盈利进一步扩大。同城即时配送分部方面,公司通过业务结构优化、精细化管理及科技驱动提升经营能力,2023年首次实现整体盈利,2024年上半年净利润扩大至0.62亿元。与此同时,顺丰控股还通过采取多项降本增效举措,包括推进多网融通,整合天网、地网的物流资源与信息网、优化业务结构以及精益管理等,提升运营效率,促进降本增效。2024年上半年,公司毛利率达到13.6%,较去年同期提升0.3个百分点。可以预见,随着新业务规模的持续增长以及降本增效效应的加持,公司的盈利水平有望进一步提升。行业景气度有望延续 国际化拓展高质量成长可期从行业的角度看,物流行业作为经济的"晴雨表",依然蕴含着巨大的市场机遇。预计2028年,全球物流支出总额将达到13.8万亿美元,2023年至2028年复合年增长率为4.4%。其中,亚洲作为全球规模最大及增长最快的物流市场,且是集中度最低的地区之一,拥有可观的增长前景,预计2023年至2028年间复合年增长率为5.5%。顺丰控股多年经营,于中国市场打下坚实发展根基,品牌形象深入人心。随后公司深耕中国及亚洲市场,不断孵化新产品、投资基础设施,市场份额持续扩大,为未来全球拓展做好准备。未来,顺丰控股计划巩固其在中国的市场领导地位,同时扩展在亚洲和全球的影响力。在亚洲市场,依托已经建立的庞大的本地物流网络、广泛的互通互联、强大的品牌知名度及团队,顺丰控股有能力复制中国成功经验,扩展高增长市场。在亚洲以外,利用公司品牌、成本优势以及综合物流能力,顺丰控股能够为全球客户提供具有价格竞争力的一站式解决方案,占据更大的市场份额。随着登陆港股资本市场,打造国际化资本运作平台,顺丰控股的综合竞争力也将在资本的助力下得到加强,为国际化战略加速推进提供有力支持。迭加持续提升其经营能力,公司高质量可持续增长可期。 Copyright 2024 亚太商讯 via SeaPRwire.com.

3 12 月, 2024

一邦携手义务工作发展局推出「渗漏纠纷义务网上调解服务」

香港, 2024年12月3日 - (亚太商讯 via SeaPRwire.com) - 为解决本港业主及住户因楼宇渗水问题所引发的矛盾和纠纷,独立非营利仲裁调解机构一邦国际网上仲调中心(「一邦」)携手义务工作发展局,于今天正式推出费用全免的「渗漏纠纷义务网上调解服务」,致力为市民提供高效、经济的网上调解服务,协助解决社区渗水纠纷,促进邻里和谐及实现社区共融。该服务计划获得由食物环境卫生署及屋宇署组成的「联合办事处」(俗称「渗水办」)的大力支持,当渗水问题发生后,有关双方可以在任何阶段随时同意进行调解, 届时市民可通过由一邦的网站提交联络资料及调解申请书,并透过平台安排独立及中立的义务调解员进行调解。此免费调解服务务求双方以最简单、符合效益及省时的方法解决争议。积极承担社会责任,为市民解忧缓困 楼宇漏水或渗水问题是香港社区中常见的纠纷来源,当中涉及费用分摊、维修责任等不同层面的问题。此民生问题缠扰大量香港业主及住户、复杂且涉及多方责任。传统的法律程序既耗时又昂贵,难以在短时间内解决问题,涉事居民均苦不堪言。有见及此,一邦作为香港领先的非营利仲裁调解机构,积极以创新思维解决社会民生议题。本次与义务工作发展局合作、得到食物环境卫生署及屋宇署支持推出的免费义务网上调解服务,弥补了这一项法律服务空白,为有需要的市民提供了一个高效、经济、便捷的解决途径。高效解决渗水纠纷,网上调解优势显著 一邦的调解规则及网上争议解决平台突破了传统调解的时间和空间限制,让当事人可以随时随地参与调解过程,相比繁琐的诉讼程序,网上调解快捷高效,双方无需经历冗长的法律程序及昂贵的诉讼费用,降低解决争议的门槛。这种灵活的服务模式符合现代都市生活繁忙的市民的需求、构建和谐社区。此外,调解过程由当事人主导,当事人拥有对结果的更多控制权,双方能共同商定解决方案,而非将决策权完全交予法庭。同时,调解强调公平和理解,能缓解双方的紧张情绪,避免冲突升级,并在一定程度上保护双方的邻里关系。而专业调解员作为第三方,秉持中立态度,协助双方探讨可行的解决方案,让各方安心。创新法律科技,助力构建和谐未来 一邦主席苏绍聪博士表示:「我们一直以服务社会、推动可持续发展为己任,运用创新科技和专业知识回馈社会。此次能够与义务工作发展局合作,得到食物环境卫生署及屋宇署支持,推出免费的『渗漏纠纷义务网上调解服务』,不仅解决民生问题,更为建设和谐共融的社会环境提供了新思路。未来,一邦将继续与政府及其他机构紧密合作,为更多市民提供优质、高效的争议解决服务。」义务工作发展局主席彭韵僖女士表示:「我们一直关注市民需求,并致力承担枢纽角色,与社会各界建立伙伴关系以解决民生问题。我们招募配对有心服务社会的专业调解员义工,透过一邦的网上法律平台,向相关业主或租户提供免费的调解服务,相信能在解决楼宇渗漏争议发挥关键作用。我们期待透过是次创新措施,促进社区和谐,使市民都能安居乐业。」根据「渗水办」的数字显示,过去5年平均每年接获逾4万宗涉及单位渗漏的投诉,成功找出渗水源头并完成调查的个案数目,平均每年约有5,800宗,占整体投诉约14.5%。截至2023年9月,仍在进行调查的个案数目约为1万宗,而在2020至2022年间约有30%的个案未能于90个工作天内完成调查并告知举报人调查结果。一邦携手义务工作发展局推动的「渗漏纠纷义务网上调解服务」,相信能够有效缩减处理渗水个案的时间,提高效率以解决市民的生活问题,并在促进社区和谐、减少社会矛盾方面发挥更大作用。「渗漏纠纷义务网上调解服务」网页:https://ebram.org/Water_Seepage_POM_Scheme/?language=tc Copyright 2024 亚太商讯 via SeaPRwire.com.

3 12 月, 2024

Fujitsu entrepreneurship program spins out first start-up company

KAWASAKI, Japan, Dec 3, 2024 - (JCN Newswire via SeaPRwire.com) - Fujitsu today announced that it has spun out blue carbon services company BLUABLE Ltd. from its entrepreneurship program Fujitsu Innovation Circuit (FIC.) The company, established as a startup in October 2024, is the first company to be successfully generated by the program.BLUABLE has secured funding from Spinout Capital Fund No.1, a Japanese venture capital fund for corporate spinouts, in November 2024. The funds will be used to validate the product-market fit of the products and services developed.BLUABLE aims to promote carbon neutrality and contribute to the sustainability of the marine environment by providing services related to blue carbon, i.e., carbon captured and stored in the world's ocean and coastal ecosystems.A significant amount of blue carbon is stored in seaweed, and a rise in seawater temperatures has caused a loss of seaweed beds and damage to seawater quality and conditions.BLUABLE produces kits to encourage seaweed bed growth. The kits are made from a material which seaweed can easily adhere to and no heavy equipment is needed to place the kits in the ocean, saving resources as compared to current cultivation methods. In addition, BLUABLE measures the blue carbon secured through utilization of its kits and uses the data to apply for J Blue Credits (1). Currently, BLUABLE is conducting field trials for seaweed bed cultivation at 16 undersea locations in Japan.The company plans to verify more advanced measuring techniques for blue carbon using IoT and AI.Fujitsu will provide its technology to BLUABLE, including its ocean digital twin (2), as it works toward preserving the world’s marine environment. In addition, through FIC, Fujitsu will continue contributing to a sustainable society by fostering talent and businesses that can take on the challenge of resolving societal issues.About Fujitsu Innovation Circuit (FIC)FIC, launched in November 2021 as part of Fujitsu Transformation, is a program to cultivate human resources with entrepreneurial skills and generate new businesses. FIC is comprised of the Ignition program that seeks to cultivate entrepreneurship, and the Challenge program that encourages employees to create new businesses. Over 2,500 Fujitsu employees around the world are participating in FIC.()) J Blue Credit :System of blue carbon credits issued and managed by the Japan Blue Economy (JBE) Association according to the results of an assessment and certification process implemented by an independent third-party committee.(2) Ocean digital twin :Technology that reproduces the marine environment with high precision in a digital space. Capable of collecting and modelling a wide variety of marine data.About FujitsuFujitsu’s purpose is to make the world more sustainable by building trust in society through innovation. As the digital transformation partner of choice for customers in over 100 countries, our 124,000 employees work to resolve some of the greatest challenges facing humanity. Our range of services and solutions draw on five key technologies: Computing, Networks, AI, Data & Security, and Converging Technologies, which we bring together to deliver sustainability transformation. Fujitsu Limited (TSE:6702) reported consolidated revenues of 3.7 trillion yen (US$26 billion) for the fiscal year ended March 31, 2024 and remains the top digital services company in Japan by market share. Find out more: www.fujitsu.com.Press ContactsFujitsu LimitedPublic and Investor Relations DivisionInquiries Copyright 2024 JCN Newswire via SeaPRwire.com.

3 12 月, 2024

康哲药业获得治疗痛风及高尿酸血症的1类新药独家商业化权利

深圳, 2024年12月2日 - (亚太商讯 via SeaPRwire.com) - 康哲药业控股有限公司(以下简称"康哲药业")欣然宣布,于2024年12月2日,通过其全资附属公司与杭州新元素药业有限公司(以下称"新元素药业",曾用名"江苏新元素医药科技有限公司")就治疗痛风及高尿酸血症的1类新药ABP-671("产品")签订独家商业化协议("协议")。根据协议,康哲药业获得产品在中国大陆、香港特别行政区及澳门特别行政区的独家商业化权利。合作期限开始于协议生效之日,自产品首次在中国大陆获批上市起拥有十年的授权期限("授权期限")。授权期限届满后,根据协议约定的特定条件,授权期限可自动续期十年。ABP-671是用于治疗痛风及高尿酸血症的化药1类创新药,目前正分别在中国和境外开展关于痛风的2b/3期临床试验,产品通过抑制尿酸盐转运蛋白1(URAT1),降低肾脏对尿酸的重吸收。在已经完成的两项2期临床试验结果显示,ABP-671多个剂量组(1mg至12mg)表现出良好的药效和安全性。该产品2mg每天单次给药,其药效可能相当于或优于苯溴马隆和非布司他最高剂量80mg的药效。尿酸下降可维持全天候24小时,没有出现严重的安全性问题。产品有望为痛风及高尿酸血症患者带来疗效更优、安全性更高的治疗选择[1]。与ABP-671相关的化合物和用途方面的多个专利已在中国获得授权。高尿酸血症是指成人在正常嘌呤饮食情况下,非同日2次空腹血尿酸水平超过420μmol/L (7.0mg/dL)。高尿酸血症患者出现尿酸盐晶体沉积,导致痛风性关节炎,称为痛风。高尿酸血症及痛风可引起关节软骨、骨质、肾脏以及血管壁等急慢性炎症损伤,导致心、脑、肾等多器官损害。《2021中国高尿酸及痛风趋势白皮书》数据显示,我国高尿酸血症的总体的患病率为13.3%,高尿酸血症患病人数约1.77亿人,痛风总体发病率为1.1%,患病人数约为1,466万。据弗若斯特沙利文分析,未来中国高尿酸血症和痛风患病人数会持续增加,将在2030年分别达到2.4亿人、5,220万人。目前我国临床上常用的降尿酸药物主要包括抑制尿酸合成和促进尿酸排泄两类,由于已上市降尿酸药物在疗效和安全性上仍存在一定的局限性,如导致肾衰竭、心脏猝死或严重肝脏毒性等。中国痛风及高尿酸血症患者对高效安全的降尿酸药物仍然有迫切的需求。ABP-671是当前痛风及高尿酸血症治疗中潜在疗效优、安全性好的产品。通过本次合作引进,填补了康哲药业痛风治疗产品的空白。痛风及高尿酸血症既属于风湿疾病又属于慢性代谢性疾病,与康哲药业心脑血管/消化业务的战略布局,以及在售品种的网络资源高度契合。ABP-671如未来获批上市,在风湿免疫科可与在售产品美泰彤(甲氨蝶呤注射液),在内分泌科和骨科可与益盖宁(依降钙素注射液)在专家网络与市场资源方面协同。基于未满足的临床需求和产品预期扎实的临床数据,期待ABP-671的临床开发工作顺利推进,使相关适应症患者尽快从创新疗法中获益。关于新元素药业新元素药业创办于2012年3月,专注于代谢和炎症领域疾病中具有全球商业价值和全球竞争力的创新药的研发。新元素药业主要核心团队人员来自美国,具有广泛的创新药物的研发经验,过去几年新元素药业取得了显著的发展成果。其核心产品ABP-671正处于后期临床研发阶段,用于治疗慢性痛风;另一个小分子创新药物ABP-745用于抗炎自免领域适应症,已完成1期临床,表现出良好的PK和安全性,即将进入2期临床。有关新元素药业及其产品的更多信息,请访问其官方网站:https://www.atombp.com/。关于康哲药业康哲药业是一家链接医药创新与商业化,把控产品全生命周期管理的开放式平台型企业,致力于提供有竞争力的产品和服务,满足尚未满足的医疗需求。康哲药业专注于全球首创(FIC)及同类最优(BIC)的创新产品,并高效推进创新产品临床研究开发和商业化进程,赋能科研成果向诊疗实践的持续转化,造福患者。康哲药业聚焦专科领域,拥有被验证的商业化能力,广泛的渠道覆盖和多疾病领域专家资源,核心在售产品已获领先的学术与市场地位。康哲药业围绕优势专科领域不断纵深发展,以巩固心脑血管/消化业务竞争力,并将皮肤医美、眼科业务独立运营,培育专科小领域的大龙头,提升专科规模效率。同时业务版图拓展至东南亚市场,着力成为全球药企进军东南亚市场的"桥头堡",助力康哲药业高质量持续健康发展。参考文献:1.产品2期临床试验结果已发布,详情如下:https://www.atombp.com/2023/03/01/atom-bioscience-announces-positive-results-of-phase-2a-china-clinical-trial-of-its-urat1-inhibitor-for-chronic-gout/康哲药业免责与前瞻性声明本新闻无意向您做任何产品的推广,非广告用途。本新闻不对任何药品和医疗器械和/或适应症作推荐。若您想了解具体疾病诊疗信息,请遵从医生或其他医疗卫生专业人士的意见或指导。医疗卫生专业人士作出的任何与治疗有关的决定应根据患者的具体情况并遵照药品说明书。由康哲药业编制的此新闻不构成购买或认购任何证券的任何要约或邀请,不形成任何合约或任何其他约束性承诺的依据或加以依赖。本新闻由康哲药业根据其认为可靠之资料及数据编制,但康哲药业并无进行任何说明或保证、明述或暗示,或其他表述,对本新闻内容的真实性、准确性、完整性、公平性及合理性不应加以依赖。本新闻中讨论的若干事宜可能包含涉及康哲药业的市场机会及业务前景的陈述,该等陈述分别或统称为前瞻性声明。该等前瞻性声明并非对未来表现的保证,存在已知及未知的风险、不明朗性及难以预知的假设。康哲药业并不采纳本新闻包含的第三方所做的任何前瞻性声明及预测,康哲药业对该等第三方声明及预测不承担责任。 Copyright 2024 亚太商讯 via SeaPRwire.com.

3 12 月, 2024

MHI Receives Order to Supply 24 MOX Fuel Assemblies for Unit 3 of Ikata Nuclear Power Station, Shikoku Electric Power Co. Inc.

TOKYO, Dec 2, 2024 - (JCN Newswire via SeaPRwire.com) - Mitsubishi Heavy Industries, Ltd. (MHI) has received an order from Shikoku Electric Power Co. Inc. (Shikoku) to supply 24 MOX(1) fuel assemblies for Unit 3 of the Ikata Nuclear Power Station, subsequent to the order received in October from Kyushu Electric Power Co. Inc. for Unit 3 of the Genkai Nuclear Power Station. Under this contract, MHI will perform design of MOX fuel, and have components such as cladding tubes manufactured by Mitsubishi Nuclear Fuel Co., Ltd. (MHI Group) provided to Orano, who will fabricate MOX fuel assemblies at its MELOX plant in France.MHI has previously supplied 57 MOX fuel assemblies to Japanese utilities, and will supply high-quality MOX fuel by leveraging its past experience and technical capability. MOX fuel will enable Shikoku to utilize plutonium extracted by reprocessing spent fuel, and MHI will contribute to steady promotion of Shikoku's "Plu-Thermal" plan(2) through the supply of MOX fuel.(1) MOX (Mixed Oxide Fuel) is nuclear fuel made of plutonium extracted by reprocessing of spent fuel, and uranium.(2) The "Plu-Thermal" plan is to utilize MOX fuel in light water reactors.Tags: nuclear power generation,MOX fuel assemblyAbout MHI GroupMitsubishi Heavy Industries (MHI) Group is one of the world’s leading industrial groups, spanning energy, smart infrastructure, industrial machinery, aerospace and defense. MHI Group combines cutting-edge technology with deep experience to deliver innovative, integrated solutions that help to realize a carbon neutral world, improve the quality of life and ensure a safer world. For more information, please visit www.mhi.com or follow our insights and stories on spectra.mhi.com. Copyright 2024 JCN Newswire via SeaPRwire.com.

3 12 月, 2024

共建一带一路:吉尔吉斯斯坦国家财政部首场推介会暨非交易性路演成功举行

香港, 2024年12月3日 - (亚太商讯 via SeaPRwire.com) - 2024年12月2日,在"一带一路"倡议的背景下,由天风国际证券集团有限公司(以下简称"天风国际")与中信银行(国际)有限公司(以下简称"信银国际")联合主办的首场"一带一路"黄金线系列金融推介会 - 吉尔吉斯斯坦国家财政部推介会暨非交易性路演于今日在香港圆满举行。本次活动吸引了众多国际投资机构及金融行业领袖出席。吉尔吉斯斯坦作为最早支持和参与"一带一路"倡议的国家之一,近年来与中国的经贸合作关系日益密切。近期,天风国际与吉尔吉斯斯坦国家财政部签订合作备忘录,成为首家与吉尔吉斯斯坦国家财政部建立合作关系的驻港中资券商。双方将就共同推动人民币国际化愿景,服务实体经济,助力高质量发展,为维持并进一步巩固香港作为国际金融中心的地位,展开更广泛的合作。本次活动邀请了多位重量级嘉宾,包括吉尔吉斯斯坦国家财政部副部长Amanbaev Umutzhan Mominovich先生、政府借贷部主任Abdybapov Abdanbek Abdybapovich先生、香港特别行政区政府财经事务及库务局副局长陈浩濂太平绅士,以及天风国际行政总裁邹传先生和信银国际高级董事、债券资本市场、财资及环球市场Andy Siow先生。会上,嘉宾们分享了吉尔吉斯斯坦在参与国际金融市场的发展机遇与其投资前景,共同探讨了双方互利共赢的合作着力点。陈浩濂副局长在致辞中表示:"香港作为全球主要国际金融中心,具备资本与信息的自由流动、稳健的普通法制度以及单一税制等核心优势,同时香港与中国内地市场联系紧密,在促进人民币国际化和推动'一带一路'倡议中发挥着关键作用。而吉尔吉斯斯坦作为'一带一路'倡议下的重要合作伙伴,毫无疑问,也是香港在中亚地区的重要贸易伙伴。感谢天风国际的精心组织和吉尔吉斯斯坦代表团的到访,今天我们齐聚一堂,探讨如何进一步加强中亚与香港之间的经济合作。我们期待未来与吉尔吉斯斯坦的合作将为两国经济增长注入新的动力,推动'一带一路'国家之间的多层次合作,进一步促进区域经济的可持续发展。"自2024年9月1日起,人民币已正式列入吉尔吉斯斯坦官方每日公布汇率的货币名单,与美元、欧元、俄罗斯卢布和哈萨克斯坦坚戈一起,成为吉尔吉斯斯坦每日公布汇率的货币,这一举措进一步深化了两国在经济与金融领域的合作。吉尔吉斯斯坦国家财政部副部长Amanbaev Umutzhan Mominovich先生在会上表示:"人民币成功纳入吉尔吉斯斯坦官方每日公布汇率的货币名单,标志着两国经济合作进入了新的阶段。这不仅为国际投资者提供了更多便利,也为吉尔吉斯斯坦的金融市场发展赋能。我们希望通过此次推介会,与更多国际投资机构建立联系,共同推动区域经济的可持续发展。"香港作为国际金融中心,同时也是粤港澳大湾区的核心城市,凭借多样的融资渠道和与国家战略的深度对接,在"一带一路"倡议中发挥了重要的桥梁作用。作为此次活动的联合主办方之一,天风国际行政总裁邹传先生在致辞中提到:"'一带一路'倡议为经济一体化和发展提供了巨大机遇,推动亚欧、中东乃至更广泛地区的贸易往来。香港作为中国市场联通世界的重要窗口,同时也是人民币国际化的关键枢纽,促进人民币在贸易和投资中的使用,支持'一带一路'项目的融资与汇率风险管理。随着人民币国际化的推进,香港正稳步成为全球领先的融资中心。在探索未来机遇的同时,期待今日的活动与市场洞察的深入分享,对吉尔吉斯斯坦发展进程以及中亚经济带来积极、深远的影响。"后续,天风国际联合信银国际将陪同吉尔吉斯斯坦国家财政部于12月3日至6日期间,陆续在上海和北京继续举办系列非交易性路演活动,进一步深化吉尔吉斯斯坦与中国金融市场的联系。此次香港推介会的成功举办标志着两国在经济领域合作迈向新高度,为"一带一路"倡议的高质量发展注入了新动能。 Copyright 2024 亚太商讯 via SeaPRwire.com.

3 12 月, 2024

Honda Introduces AI-powered Social Robot, Haru, to University Hospital in Spain

TOKYO, Dec 2, 2024 - (JCN Newswire via SeaPRwire.com) - Honda Research Institute Japan Co., Ltd. (HRI-JP), a Honda R&D subsidiary responsible for the research of cutting-edge technologies, has officially introduced its AI-powered social robot named “Haru” at the Virgen del Rocío University Hospital (HUVR) in Seville, Spain, to enhance the well-being of children while in the hospital.At the Annual Gala against Childhood Cancer, held on November 28 local time, at Casino de la Exposicion in Seville, Spain, the HUVR introduced Haru as one of the projects HUVR is implementing to improve the lives of children with cancer, who are in the hospital for long-term treatment.AI-powered social robot, HaruHRI-JP has been developing Haru, an AI-powered social robot, as a “tangible AI system” striving to realize a society where robots coexist as partners of people and to facilitate communications that create connections among people. Haru was designed to be a social robot that makes people smile through expressive communications and forms empathetic relationships with people. As a compact desk-top robot with a total height of 30cm (12 inches), Haru can be placed on a table to engage in communications with people.Haru obtains biometric information of the user, such as facial expressions and voice tones, through its built-in camera and microphones, then analyzes the information obtained to understand the user’s current state, and interacts with each user in accordance with the result of analysis, using empathetic expressions and emotionally supportive responses. Moreover, Haru can also be linked to a wristwatch-type wearable sensor worn by the user and analyze the user’s conditions in greater detail.Furthermore, as a robot, Haru does not have any human attributes such as gender, race or nationality, and is always capable of communicating from a neutral perspective, enabling Haru to effectively facilitate communication beyond generational and cultural differences, especially in group communication.HUVR had been conducting a demonstration experiment using Haru in the pediatric oncology ward of the hospital since 2021 for the purpose of enhancing both the clinical and emotional care of young patients. Since the results of the experiment have confirmed a certain level of positive effects on children with cancer, the official decision was made to advance the project with full-fledged utilization of Haru, introducing 10 units to be used in various situations in the children’s daily lives in the pediatric oncology unit.Key results of the demonstration experiment at the HUVR1. Assisting emotional and cognitive assessmentsHaru has been assisting the hospital’s neuropsychologists in conducting emotional and cognitive assessments. Using AI technology, Haru communicates with children; analyzes their biometric information, such as facial expressions and voice tones, obtained through its built-in cameras and microphones; and assist neuropsychologists in conducting emotional and cognitive assessments.Due to the amount of time the assessment takes, there is a limit to the number of assessments the neuropsychologists can conduct each year: the number had been limited to 510 per year including follow-up consultations until now. With the introduction of Haru, the number of assessments the hospital can conduct each year is expected to increase to as many as 4,500.2. Assisting rehabilitation activitiesHaru has been supporting intellectual and physical rehabilitation programs provided to young patients at the hospital. Haru learns the rehabilitation programs and can guide the children through the process while engaging them in conversation. The demonstration experiment showed that 95% of children were more actively engaged in rehabilitation while receiving guidance from Haru, compared to conventional human guides.3. Serving as a companion in playrooms and hospital roomsYoung patients who undergo long-term hospital stays for treatment spend a lot of time alone in their rooms. By communicating with the children, Haru can offer entertainment and cognitive stimulation, and help to soothe their feeling of loneliness, contributing to the enhancement of emotional care the hospital provides.4. Offering educational supportHaru connects the hospital rooms of the children who have not been able to attend school with the classrooms of their schools online, and facilitates the communication as an intermediary. This provides children at the hospital with opportunity to receive education together with children in the classroom and to interact with each other among children.Comments by the Virgen del Rocío University Hospital in Seville (HUVR)“We have been conducting joint research with HRI-JP for several years now, and gained wonderful results. We have identified that Haru holds great potential in bringing happiness to children. Typically, technologies used in hospitals focus on medical treatments or physical well-being. However, Haru has positive psychological effect of lightening the mood of our young patients and also contributes to the well-being of the hospital as a whole. The support that Haru provides, enabling children under hospital care to feel more happiness and connection with others, is unique only to Haru and offers valuable benefits not found in traditional medical care. We believe that Haru is a groundbreaking presence that creates an environment where young patients can enjoy their time here at our hospital.”Comments by Satoshi Shigemi, Honda Research Institute Japan Co., Ltd. (HRI-JP)“Based on the founding spirit of Honda, ‘using our technology to help people’ and ‘understanding people is the very essence of Honda monozukuri (art of making things),’ Honda Research Institute has been conducting research into cutting-edge technologies which have the potential to enhance positive psychological effects of people and the overall well-being of society. We are delighted by the result of our joint research with Virgen del Rocío University Hospital that shows Haru has been able to be a companion to the children at the hospital, lifting up their spirits, and bringing smiles to their faces. Moving forward, we will continue our efforts to further advance Haru as a robot which can co-exist with people 24/7 and be more helpful to young patients as well as all hospital staff to contribute to the well-being of the hospital a whole.”About Honda Research Institute (HRI)HRI was established in 2003 as a research operation which will go beyond the framework of the traditional business domain of the Honda Group and take on challenges to address issues facing humanity. Each of three HRI operations, located in Japan, the United States, and Germany, is engaged in “frontier research” with a focus on next-generation AI, including the exploration of new technologies such as quantum technology. By using Pasteur's Quadrant approach to research, which calls for the simultaneous pursuit of principles, or science, and real-world applications, HRI is striving to quickly give shape to new technologies and ideas, and create new value that can be useful to society. The research outcomes generated by HRI will lead toward the development of future Honda technologies in a wide range of technology fields, including but not limited to the areas of safety, the environment and next-generation mobility.Honda Research Institute Japan Co., Ltd. (HRI-JP), a Honda R&D subsidiary responsible for the research of cutting-edge technologies, has officially introduced its AI-powered social robot named “Haru” at the Virgen del Rocío University Hospital (HUVR) in Seville, Spain, to enhance the well-being of children while in the hospital.At the Annual Gala against Childhood Cancer, held on November 28 local time, at Casino de la Exposicion in Seville, Spain, the HUVR introduced Haru as one of the projects HUVR is implementing to improve the lives of children with cancer, who are in the hospital for long-term treatment.AI-powered social robot, HaruHRI-JP has been developing Haru, an AI-powered social robot, as a “tangible AI system” striving to realize a society where robots coexist as partners of people and to facilitate communications that create connections among people. Haru was designed to be a social robot that makes people smile through expressive communications and forms empathetic relationships with people. As a compact desk-top robot with a total height of 30cm (12 inches), Haru can be placed on a table to engage in communications with people.Haru obtains biometric information of the user, such as facial expressions and voice tones, through its built-in camera and microphones, then analyzes the information obtained to understand the user’s current state, and interacts with each user in accordance with the result of analysis, using empathetic expressions and emotionally supportive responses. Moreover, Haru can also be linked to a wristwatch-type wearable sensor worn by the user and analyze the user’s conditions in greater detail.Furthermore, as a robot, Haru does not have any human attributes such as gender, race or nationality, and is always capable of communicating from a neutral perspective, enabling Haru to effectively facilitate communication beyond generational and cultural differences, especially in group communication.HUVR had been conducting a demonstration experiment using Haru in the pediatric oncology ward of the hospital since 2021 for the purpose of enhancing both the clinical and emotional care of young patients. Since the results of the experiment have confirmed a certain level of positive effects on children with cancer, the official decision was made to advance the project with full-fledged utilization of Haru, introducing 10 units to be used in various situations in the children’s daily lives in the pediatric oncology unit.Key results of the demonstration experiment at the HUVR1. Assisting emotional and cognitive assessmentsHaru has been assisting the hospital’s neuropsychologists in conducting emotional and cognitive assessments. Using AI technology, Haru communicates with children; analyzes their biometric information, such as facial expressions and voice tones, obtained through its built-in cameras and microphones; and assist neuropsychologists in conducting emotional and cognitive assessments.Due to the amount of time the assessment takes, there is a limit to the number of assessments the neuropsychologists can conduct each year: the number had been limited to 510 per year including follow-up consultations until now. With the introduction of Haru, the number of assessments the hospital can conduct each year is expected to increase to as many as 4,500.2. Assisting rehabilitation activitiesHaru has been supporting intellectual and physical rehabilitation programs provided to young patients at the hospital. Haru learns the rehabilitation programs and can guide the children through the process while engaging them in conversation. The demonstration experiment showed that 95% of children were more actively engaged in rehabilitation while receiving guidance from Haru, compared to conventional human guides.3. Serving as a companion in playrooms and hospital roomsYoung patients who undergo long-term hospital stays for treatment spend a lot of time alone in their rooms. By communicating with the children, Haru can offer entertainment and cognitive stimulation, and help to soothe their feeling of loneliness, contributing to the enhancement of emotional care the hospital provides.4. Offering educational supportHaru connects the hospital rooms of the children who have not been able to attend school with the classrooms of their schools online, and facilitates the communication as an intermediary. This provides children at the hospital with opportunity to receive education together with children in the classroom and to interact with each other among children.Comments by the Virgen del Rocío University Hospital in Seville (HUVR)“We have been conducting joint research with HRI-JP for several years now, and gained wonderful results. We have identified that Haru holds great potential in bringing happiness to children. Typically, technologies used in hospitals focus on medical treatments or physical well-being. However, Haru has positive psychological effect of lightening the mood of our young patients and also contributes to the well-being of the hospital as a whole. The support that Haru provides, enabling children under hospital care to feel more happiness and connection with others, is unique only to Haru and offers valuable benefits not found in traditional medical care. We believe that Haru is a groundbreaking presence that creates an environment where young patients can enjoy their time here at our hospital.”Comments by Satoshi Shigemi, Honda Research Institute Japan Co., Ltd. (HRI-JP)“Based on the founding spirit of Honda, ‘using our technology to help people’ and ‘understanding people is the very essence of Honda monozukuri (art of making things),’ Honda Research Institute has been conducting research into cutting-edge technologies which have the potential to enhance positive psychological effects of people and the overall well-being of society. We are delighted by the result of our joint research with Virgen del Rocío University Hospital that shows Haru has been able to be a companion to the children at the hospital, lifting up their spirits, and bringing smiles to their faces. Moving forward, we will continue our efforts to further advance Haru as a robot which can co-exist with people 24/7 and be more helpful to young patients as well as all hospital staff to contribute to the well-being of the hospital a whole.”About Honda Research Institute (HRI)HRI was established in 2003 as a research operation which will go beyond the framework of the traditional business domain of the Honda Group and take on challenges to address issues facing humanity. Each of three HRI operations, located in Japan, the United States, and Germany, is engaged in “frontier research” with a focus on next-generation AI, including the exploration of new technologies such as quantum technology. By using Pasteur's Quadrant approach to research, which calls for the simultaneous pursuit of principles, or science, and real-world applications, HRI is striving to quickly give shape to new technologies and ideas, and create new value that can be useful to society. The research outcomes generated by HRI will lead toward the development of future Honda technologies in a wide range of technology fields, including but not limited to the areas of safety, the environment and next-generation mobility.HRI-JP has been developing Haru, an AI-powered social robot, as a “tangible AI system” striving to realize a society where robots coexist as partners of people and to facilitate communications that create connections among people. Haru was designed to be a social robot that makes people smile through expressive communications and forms empathetic relationships with people. As a compact desk-top robot with a total height of 30cm (12 inches), Haru can be placed on a table to engage in communications with people.Haru obtains biometric information of the user, such as facial expressions and voice tones, through its built-in camera and microphones, then analyzes the information obtained to understand the user’s current state, and interacts with each user in accordance with the result of analysis, using empathetic expressions and emotionally supportive responses. Moreover, Haru can also be linked to a wristwatch-type wearable sensor worn by the user and analyze the user’s conditions in greater detail.Furthermore, as a robot, Haru does not have any human attributes such as gender, race or nationality, and is always capable of communicating from a neutral perspective, enabling Haru to effectively facilitate communication beyond generational and cultural differences, especially in group communication.HUVR had been conducting a demonstration experiment using Haru in the pediatric oncology ward of the hospital since 2021 for the purpose of enhancing both the clinical and emotional care of young patients. Since the results of the experiment have confirmed a certain level of positive effects on children with cancer, the official decision was made to advance the project with full-fledged utilization of Haru, introducing 10 units to be used in various situations in the children’s daily lives in the pediatric oncology unit.Key results of the demonstration experiment at the HUVR1. Assisting emotional and cognitive assessmentsHaru has been assisting the hospital’s neuropsychologists in conducting emotional and cognitive assessments. Using AI technology, Haru communicates with children; analyzes their biometric information, such as facial expressions and voice tones, obtained through its built-in cameras and microphones; and assist neuropsychologists in conducting emotional and cognitive assessments.Due to the amount of time the assessment takes, there is a limit to the number of assessments the neuropsychologists can conduct each year: the number had been limited to 510 per year including follow-up consultations until now. With the introduction of Haru, the number of assessments the hospital can conduct each year is expected to increase to as many as 4,500.2. Assisting rehabilitation activitiesHaru has been supporting intellectual and physical rehabilitation programs provided to young patients at the hospital. Haru learns the rehabilitation programs and can guide the children through the process while engaging them in conversation. The demonstration experiment showed that 95% of children were more actively engaged in rehabilitation while receiving guidance from Haru, compared to conventional human guides.3. Serving as a companion in playrooms and hospital roomsYoung patients who undergo long-term hospital stays for treatment spend a lot of time alone in their rooms. By communicating with the children, Haru can offer entertainment and cognitive stimulation, and help to soothe their feeling of loneliness, contributing to the enhancement of emotional care the hospital provides.4. Offering educational supportHaru connects the hospital rooms of the children who have not been able to attend school with the classrooms of their schools online, and facilitates the communication as an intermediary. This provides children at the hospital with opportunity to receive education together with children in the classroom and to interact with each other among children.Comments by the Virgen del Rocío University Hospital in Seville (HUVR)“We have been conducting joint research with HRI-JP for several years now, and gained wonderful results. We have identified that Haru holds great potential in bringing happiness to children. Typically, technologies used in hospitals focus on medical treatments or physical well-being. However, Haru has positive psychological effect of lightening the mood of our young patients and also contributes to the well-being of the hospital as a whole. The support that Haru provides, enabling children under hospital care to feel more happiness and connection with others, is unique only to Haru and offers valuable benefits not found in traditional medical care. We believe that Haru is a groundbreaking presence that creates an environment where young patients can enjoy their time here at our hospital.”Comments by Satoshi Shigemi, Honda Research Institute Japan Co., Ltd. (HRI-JP)“Based on the founding spirit of Honda, ‘using our technology to help people’ and ‘understanding people is the very essence of Honda monozukuri (art of making things),’ Honda Research Institute has been conducting research into cutting-edge technologies which have the potential to enhance positive psychological effects of people and the overall well-being of society. We are delighted by the result of our joint research with Virgen del Rocío University Hospital that shows Haru has been able to be a companion to the children at the hospital, lifting up their spirits, and bringing smiles to their faces. Moving forward, we will continue our efforts to further advance Haru as a robot which can co-exist with people 24/7 and be more helpful to young patients as well as all hospital staff to contribute to the well-being of the hospital a whole.”About Honda Research Institute (HRI)HRI was established in 2003 as a research operation which will go beyond the framework of the traditional business domain of the Honda Group and take on challenges to address issues facing humanity. Each of three HRI operations, located in Japan, the United States, and Germany, is engaged in “frontier research” with a focus on next-generation AI, including the exploration of new technologies such as quantum technology. By using Pasteur's Quadrant approach to research, which calls for the simultaneous pursuit of principles, or science, and real-world applications, HRI is striving to quickly give shape to new technologies and ideas, and create new value that can be useful to society. The research outcomes generated by HRI will lead toward the development of future Honda technologies in a wide range of technology fields, including but not limited to the areas of safety, the environment and next-generation mobility. Copyright 2024 JCN Newswire via SeaPRwire.com.

2 12 月, 2024

DENSO to Exhibit at “Automechanika Dubai 2024”

KARIYA, JAPAN, Dec 2, 2024 - (JCN Newswire via SeaPRwire.com) - DENSO Sales Middle East & North Africa (DSMN), a group company of DENSO Corporation, will participate in “Automechanika Dubai 2024,” held at the Dubai World Trade Centre from December 10 to 12, 2024.Established in 2010 in Dubai, DSMN serves the Middle East and North Africa regions by offering aftermarket products and services. In these regions, motorization is advancing, and vehicles tend to have longer operational lifespans. DSMN strives to provide customers and users with peace of mind and trust through high-quality products and services, contributing to the realization of a sustainable mobility society.Automechanika Dubai is the largest automotive aftermarket trade show in the Middle East and Africa. This year, over 2,200 exhibitors are expected to participate. Many visitors are businesses seeking to establish partnerships with exhibitors, and attendance is anticipated to exceed last year’s 52,469 visitors from 161 countries. The event offers an excellent opportunity to expand business possibilities, not only in the Middle East and Africa but also in regions such as West Asia and Central Asia.Through this exhibition, DSMN aims to showcase aftermarket solutions and explore opportunities for advanced technology-based products and services. Additionally, DSMN will deepen interactions with customers and partner companies, identifying new needs and pursuing tailored solutions to address regional challenges.Booth ImageDSMN Website: https://denso.ae/Please see here for more details on DSMN’s booth: https://denso.ae/events/join-us-at-automechanika-dubai-2024-celebrating-75-years-of-innovation Copyright 2024 JCN Newswire via SeaPRwire.com.

2 12 月, 2024

Fujitsu expands global strategic collaboration agreement with AWS to promote customer digital transformation across industries

KAWASAKI, Japan, Dec 2, 2024 - (JCN Newswire via SeaPRwire.com) - Fujitsu today announced that it has signed a three-year global strategic collaboration agreement (SCA) with Amazon Web Services (AWS) (1). This collaboration, officially concluded on November 29, expands the existing agreements in the mobility, finance, and retail sectors to a broader range of industries .Through this collaboration, Fujitsu will combine its expertise in systems integration and its Fujitsu Uvance offering to solve societal issues with AWS’s cloud services and cloud-native architecture to accelerate customers' digital transformation (DX) and address business challenges.Additionally, with AWS’s skills training, Fujitsu aims to strengthen its delivery system by increasing the number of Fujitsu engineers who have AWS certifications from approximately 7,000 to 12,000 over the next three years and double the number of customer deals to over 800 compared to the past 3-year SCA period.BackgroundWith the target year of 2030 for achieving the United Nations Sustainable Development Goals (SDGs) approaching, Fujitsu is promoting Fujitsu Uvance, its business model that aims to increase business growth and solve societal issues.Fujitsu Uvance leverages Fujitsu's extensive technology and industry expertise to seamlessly integrate fragmented processes and data, with the aim of creating new solutions and insights for customers. To achieve this, it is crucial to move away from legacy systems and strategically utilize cloud computing with partners. By expanding strategic collaboration with AWS, the world’s most comprehensive and broadly adopted cloud, and creating a combined solution that address customers business challenges and opportunities, Fujitsu will drive digital transformation across industries.Overview of the Initiatives1. Strengthening Fujitsu’s AWS cloud migration support servicesIn addition to having customers core systems run on their mainframes and UNIX servers, which was a strategic target of the legacy modernization collaboration announced in March 2024, the two companies will strengthen migration support services for broader on-premise systems to move onto AWS. Fujitsu will provide a comprehensive set of cloud-native system integration and operation support services through Fujitsu Cloud Transformation Service and Fujitsu Cloud Managed Service (2), with technical support from AWS.2. Enhancing added value through the service integration of Fujitsu Uvance offerings and AWSFujitsu aims to enhance added value and expand the global provision of Fujitsu Uvance offerings focusing on the two pillars of Trusted Society for a prosperous and sustainable society and Digital Shifts to support customers' data-driven strategies. As part of this effort, Fujitsu has started linking the Digital Shifts offering with its Fujitsu Kozuchi AI service and Amazon Bedrock, AWS's generative AI service. For example, Fujitsu Data Intelligence Premium, an operation platform that utilizes data and AI, analyzes production line data from factories, uses AI to detect risk signs and propose countermeasures based on past cases, and converts past inspection reports into reusable structured data to visualize and share accumulated know-how in facility maintenance work within organizations. By combining business knowledge cultivated over many years with the latest technologies such as generative AI, Fujitsu will help customers improve the efficiency and the uptime of their production processes. Demonstrations of these use cases will be showcased at the Fujitsu booth during AWS re:Invent 2024 starting today in Las Vegas, US.(3)3. Reinforcing Fujitsu’s system development and delivery capabilities by increasing the number of AWS certification holdersFujitsu aims to increase the number of Fujitsu engineers who hold AWS certifications from approximately 7,000 to 12,000 over the next three years, through AWS skills training. By increasing the number of professionals who have a deep understanding of AWS cloud services, Fujitsu will accelerate the delivery of systems that realize customers' DX, doubling the number of customer deals to over 800 compared to past 3-year SCA period.Role of Fujitsu and AWS- FujitsuLeverage its customer base and system development expertise in various industries to reach enterprise and mid-market customers.Through offerings such as legacy system modernization, cloud migration and operational support, and Fujitsu Uvance, Fujitsu will support customers' DX.- AWSAWS will strengthen its technical support for Fujitsu with its solution architects and provide advisories on the use of latest AWS services such as generative AI and cloud-native architectures for diverse use cases. AWS will also provide development environments to review latest AWS services, while also offering funds for joint sales and marketing, and AWS training and certifications for Fujitsu engineers.Yoshinami Takahashi, Vice President and COO for Uvance, Fujitsu Limited comments:“We are pleased to have concluded this global strategic collaboration with AWS. By extending our strategic collaboration to a broader range of industries, we will contribute to the digital transformation of customers across industries through legacy modernization, cloud lift and shift, and the utilization of technology and data offerings from Fujitsu Uvance together with AWS."Jaime Vallés, Vice President, Asia Pacific and Japan, Amazon Web Services comments:"Since 2012, AWS and Fujitsu have supported the digital transformation of customers in the mobility, finance, and retail sectors in Japan and worldwide. Today, we are delighted to expand our strategic collaboration with Fujitsu. Together we will broaden our Digital Transformation Experience to enable a wider range of industries and leverage our shared culture of innovation to jointly address some of the world’s biggest challenges."(1) Amazon Web Services: Headquartered in Seattle, Washington, USA, CEO Matt Garman. The collaboration was concluded with Amazon Web Services Japan GK (Head Office: Shinagawa-ku, Tokyo; President: Akihiko Shirahata).(2) Fujitsu Cloud Transformation Service and Fujitsu Cloud Managed Service: Based on Fujitsu's system design, construction, and operation know-how cultivated mainly in the enterprise domain, these services realize standardization and automation of architecture patterns, ensuring high quality while achieving cost-optimized and rapid delivery. Fujitsu adopts the "AWS Well-Architected Framework" in its delivery services, which is optimized for AWS, and has obtained the "AWS Managed Service Provider (MSP)" certification, proving the soundness and high technical capability of its AWS business.(3) AWS re:Invent: AWS’s annual global conference that starts from December 2, 2024 in Las Vegas. For more information on AWS re:Invent, please visit: https://reinvent.awsevents.com/About FujitsuFujitsu’s purpose is to make the world more sustainable by building trust in society through innovation. As the digital transformation partner of choice for customers in over 100 countries, our 124,000 employees work to resolve some of the greatest challenges facing humanity. Our range of services and solutions draw on five key technologies: Computing, Networks, AI, Data & Security, and Converging Technologies, which we bring together to deliver sustainability transformation. Fujitsu Limited (TSE:6702) reported consolidated revenues of 3.7 trillion yen (US$26 billion) for the fiscal year ended March 31, 2024 and remains the top digital services company in Japan by market share. Find out more: www.fujitsu.com.Press ContactsFujitsu LimitedPublic and Investor Relations DivisionInquiries Copyright 2024 JCN Newswire via SeaPRwire.com.

2 12 月, 2024

云顶新耀宣布中国香港卫生署正式受理伊曲莫德(VELSIPITY(R))

上海, 2024年12月2日 - (亚太商讯 via SeaPRwire.com) - 云顶新耀(HKEX 1952.HK)是一家专注于创新药研发、临床开发、制造和商业化的生物制药公司,今日宣布中国香港卫生署已正式受理伊曲莫德(VELSIPITY(R))用于治疗中重度活动性溃疡性结肠炎成人患者的新药上市许可申请(NDA)。伊曲莫德是一款每日一次口服的一线先进疗法,不仅使用方便、疗效佳,而且具有良好的安全性特征。伊曲莫德已于去年10月和今年2月先后在美国和欧盟获得新药上市批准,同时,伊曲莫德也于今年4月获得中国澳门特别行政区药物监督管理局批准上市,并于今年10月通过"港澳药械通"政策在粤港澳大湾区落地。云顶新耀首席执行官罗永庆表示:"我们非常高兴看到伊曲莫德的新药上市许可申请在中国香港获得正式受理。自身免疫性疾病是我们的重点关注领域和重要价值的潜在增长动力。到2030年,中国的溃疡性结肠炎患者人数预计将达到约100万人,超过2019年患者人数的一倍以上,存在迫切且巨大的未被满足的临床需求。伊曲莫德已在中国澳门获批,并通过"港澳药械通"政策率先在粤港澳大湾区落地。今年我们预计也将在中国大陆地区递交伊曲莫德的新药上市许可申请。期待伊曲莫德在更多地区获批,进一步扩大可及性,造福广大患者。"伊曲莫德亚太临床试验牵头研究者、世界胃肠病学会执行理事、亚太消化学会副主席、中国人民解放军空军军医大学附属西京医院吴开春教授表示:"祝贺伊曲莫德取得的这一新进展,为中国香港的患者带来了希望。伊曲莫德具有良好的获益-风险特征,这种新一代S1P受体调节剂通过每日一次口服的治疗方案,可快速起效,并达到无激素缓解、黏膜愈合,可为中重度活动性溃疡性结肠炎成人患者提供先进的治疗选择。我们期待伊曲莫德在大中华区及其他亚洲国家早日获批,为患者带来福音。"伊曲莫德的申请是基于ELEVATE UC III期注册研究(ELEVATE UC 52和ELEVATE UC 12)的结果,该研究旨在评价既往对至少一种常规治疗、生物制剂或Janus激酶(JAK)抑制剂治疗失败或不耐受的中重度活动性溃疡性结肠炎患者,每日一次服用2mg 伊曲莫德的安全性和疗效。在ELEVATE UC 52和ELEVATE UC 12中,纳入了一半以上严重活动性溃疡性结肠炎患者(mMS≥7),并有近三分之一患者曾接受过生物制剂或JAK抑制剂治疗。伊曲莫德的UC研究也是迄今唯一纳入了孤立性直肠炎患者的UC研究。这两项随机、双盲、安慰剂对照研究均达到了所有主要和关键次要终点,安全性特征与既往研究一致。在ELEVATE UC 52研究中,第12周时,接受伊曲莫德治疗的患者临床缓解率为27.0%(安慰剂组7.0%, 差异20.0%,P<0.001);第52周时,接受伊曲莫德治疗的患者临床缓解率为32.0%(安慰剂组7.0%,差异26.0%,P<0.001)。在ELEVATE UC 12研究中,接受伊曲莫德治疗的患者12周临床缓解率为26.0%(安慰剂组15.0%,差异11.0%,P<0.05)。在这两项研究中,伊曲莫德治疗组所有关键性次要终点均达到统计学意义的显著改善,包括第12周和52周的临床应答、内镜改善和组织学内镜下黏膜改善终点以及第52周的无激素缓解和持续临床缓解。伊曲莫德的安全性与之前的研究一致,最常见的不良反应是贫血和头痛。云顶新耀在亚洲地区(包括中国大陆、中国台湾和韩国)开展的伊曲莫德多中心、随机、双盲、安慰剂对照III期研究,是迄今为止完成的最大规模的亚洲中重度溃疡性结肠炎的III期注册临床研究,总计 340名中重度溃疡性结肠炎患者随机接受伊曲莫德或安慰剂治疗。此前公布的诱导期结果显示,伊曲莫德2mg治疗的患者的临床缓解率为25.0%,安慰剂治疗的患者为5.4%(差值20.4%,p<0.0001)。与安慰剂组相比,伊曲莫德治疗的患者所有关键次要终点均有显著的临床意义和统计学意义的改善。随后,今年7月份公布的维持期顶线结果证实,在经过40周的维持期治疗后,伊曲 莫德组与安慰剂组相比,主要终点和所有关键次要终点均具有显著的临床意义和统计学意义(p<0.0001)的改善,其他包括黏膜愈合、内镜恢复正常等的次要终点也均达到具有显著临床意义和统计学意义(p<0.0001)的改善。维持期治疗显示了伊曲莫德良好的安全性,安全性数据与已知特征一致,没有观察到新的安全性信号。维持期的研究结果将在近期的国际学术会议发布。关于伊曲莫德(VELSIPITY(R), etrasimod)伊曲莫德(VELSIPITY(R),etrasimod)是一种每日一次口服的高选择性鞘氨醇-1-磷酸(S1P)受体调节剂,采用优化的药理学设计,与S1P受体1、4和5结合。伊曲莫德目前已在美国、欧盟、加拿大、澳大利亚、英国、瑞士、以色列以及中国澳门和新加坡获得新药上市批准。关于云顶新耀云顶新耀是一家专注于创新药和疫苗研发、临床开发、制造和商业化的生物制药公司,致力于满足亚洲市场尚未满足的医疗需求。云顶新耀的管理团队在中国及全球领先制药企业从事过高质量研发、临床开发、药政事务、化学制造与控制(CMC)、业务发展和商业化运营,拥有深厚的专长和丰富的经验。云顶新耀已打造多款疾病首创或者同类最佳的药物组合,公司的治疗领域包括肾科疾病、感染性和传染性疾病、自身免疫性疾病。有关更多信息,请访问公司网站:www.everestmedicines.com。前瞻性声明本新闻稿所发布的信息中可能会包含某些前瞻性表述,乃基于本公司或管理层在做出表述时对公司业务运营情况及财务状况的现有看法、相信、和现有预期,可能会使用"将"、"预期"、"预测"、"期望"、"打算"、"计划"、"相信"、"预估"、"确信"及其他类似词语进行表述。这些前瞻性表述并非对未来业绩的保证,会受到风险、不确定性及其他因素的影响,有些乃超出本公司的控制范围,难以预计。因此,受我们的业务、竞争环境、政治、经济、法律和社会情况的未来变化及发展等各种因素及假设的影响,实际结果可能会与前瞻性表述所含资料有较大差别。本公司及各附属公司、各位董事、管理人员、顾问及代理未曾且概不承担更新该稿件所载前瞻性表述以反映在本新闻稿发布日后最新信息、未来项目或情形的任何义务,除非法律要求。 Copyright 2024 亚太商讯 via SeaPRwire.com.

2 12 月, 2024

MHI Receives Order from Taiwan High Speed Rail Corporation for Trackwork and Core System for New Rolling Stock Inspection Shop in Zuoying Depot

TOKYO, Dec 2, 2024 - (JCN Newswire via SeaPRwire.com) - Mitsubishi Heavy Industries, Ltd. (MHI) has received an order from Taiwan High Speed Rail Corporation to install new equipment and modify existing equipment for the expansion of the existing maintenance shop at Taiwan High Speed Rail's (THSR) Zuoying depot in southern Taiwan. MHI will design, supply and install trackwork, overhead catenary system, power supply system, and signaling system.THSR plays a key role in Taiwan's transportation infrastructure. Its annual ridership has increased from around 15 million passengers during its inaugural year in 2007, to nearly 73 million in 2023, with the cumulative ridership to date now exceeding 800 million. To better serve this increasing demand, THSR is boosting its capacity by adding 12-car train sets and expanding the associated inspection and maintenance facilities which MHI will undertake. These upgrades will enable an increase in train car operations, which will further enhance transportation convenience across Taiwan and support its economic growth.The THSR project was initially awarded to a consortium of seven Japanese companies, including MHI, in 2000. Operations were inaugurated in January 2007. MHI's involvement continued with the Nangang Extension Project(Note) and subsequent system upgrade work, and the latest contract was awarded to MHI in recognition of these and other ongoing contributions to THSR's development.Going forward, MHI will continue contributing to the THSR's development through its expertise in transportation systems and project management capabilities, further enhancing Taiwan's transportation infrastructure.For details concerning the Nangang Extension Project, refer to the following news release: www.mhi.com/news/130624en.htmlAbout MHI GroupMitsubishi Heavy Industries (MHI) Group is one of the world’s leading industrial groups, spanning energy, smart infrastructure, industrial machinery, aerospace and defense. MHI Group combines cutting-edge technology with deep experience to deliver innovative, integrated solutions that help to realize a carbon neutral world, improve the quality of life and ensure a safer world. For more information, please visit www.mhi.com or follow our insights and stories on spectra.mhi.com. Copyright 2024 JCN Newswire via SeaPRwire.com.

2 12 月, 2024